Evidence map›Paper›PMID 41920196›Full record

ReviewProtoplasma2026

Exploring the link between heavy metals detoxification and crop improvements.

Pooja Singh, Shilpy Singh, Afsana Praveen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Protoplasma, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pooja SinghDepartment of Biochemistry, Maulana Azad Medical College, New Delhi, 110002, India.
Shilpy SinghDepartment of Biotechnology & Microbiology, School of Sciences, Noida International University, Yamuna Expressway, Sector 17A, Uttar Pradesh, 203201, India.
Afsana PraveenDepartment of Biotechnology & Microbiology, School of Sciences, Noida International University, Yamuna Expressway, Sector 17A, Uttar Pradesh, 203201, India. afsana735@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heavy metal (HM)/metalloids stresses have a detrimental effect on agriculture and the ecosystem because they impose severe strains on plants, which are sessile by nature, and cause extreme economic losses. It is imperative to safeguard crop plants from HMs to maintain sustainable agriculture and meet the global need for food from an ever-increasing population. Anthropogenic activities provide a threat to agricultural soils by contaminating them with toxic HMs, which can lead to an excessive build-up of arsenic (As), aluminium (Al), cadmium (Cd), chromium (Cr), nickel (Ni), lead (Pb), and mercury (Hg) in food crops. This offers serious health concerns to humans since they got merged into the food chain. Finding ways to stop these harmful metals from building up in food requires knowing how plants absorb, move, and break down these toxins. Therefore, in the present study, universal distribution, toxicity of HMs and their emergence in the food chain, uptake and transport, detoxification mechanisms in plants, and ways of crop improvement under HM stress conditions have been explored. Conventional remediation methods can be costly, labor intensive, and environmentally disruptive. HMs/metalloids generate oxidative stress, disrupts cellular homeostasis, inhibits photosynthesis, and interfered with nutritional uptake leading to significant yield losses in plants. To cope up these stresses, plants utilize complex molecular mechanisms for resilience such as antioxidant enzymes activation, metal’ transporters upregulation, formation of metal chelation complexes, and variation of stress related genes and transcription factors. In contrast bioremediation offers a sustainable and ecofriendly alternative by leveraging the detoxification capabilities of plants, microbes, and their symbiotic interactions. Practices like phytoremediation, microbial-assisted remediation, and combined approaches involving nanobiochar, biostimulants, and organic amendments have established promising outcomes in restoring HMs/metalloids contaminated soil. In this study we have attempted to outline the different HMs/metalloids toxicity, uptake, and detoxification in one place. This would reduce the obstacles to agricultural output and the world’s food demands while also assisting in understanding the better HMs’ resilience in crop plants.

Indexed as

Crops, AgriculturalMetals, HeavySoil PollutantsMetals, HeavySoil PollutantsCrop plantsDetoxificationHeavy metalsROSToxicityTransport

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.