Evidence map›Paper›PMID 41921878›Full record

ArticleJournal of affective disorders2026

Betrayal as consequence and catalyst: Longitudinal and reciprocal relations with PTSD and depression during ongoing conflict.

Rony Kapel Lev-Ari, Shilat Haim-Nachum, John C Markowitz, Chana T Fisch, Amit Lazarov, Yossi Levi-Belz, Ido Lurie, Milton L Wainberg, Shlomo Mendlovic, Yuval Neria and 1 more

Abstract read
In one paragraph

Article in Journal of affective disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rony Kapel Lev-AriNew York State Psychiatric Institute and Department of Psychiatry, New York, NY, United States of America; Columbia University Vagelos College of Physicians & Surgeons, New York, NY, United States of America. Electronic address: Kapel.Lev-ari@nyspi.columbia.edu.
Shilat Haim-NachumSchool of Social Work, Tel Aviv University, Tel Aviv, Israel.
John C MarkowitzNew York State Psychiatric Institute and Department of Psychiatry, New York, NY, United States of America; Columbia University Vagelos College of Physicians & Surgeons, New York, NY, United States of America.
Chana T FischNew York State Psychiatric Institute and Department of Psychiatry, New York, NY, United States of America; Columbia University Vagelos College of Physicians & Surgeons, New York, NY, United States of America.
Amit LazarovSchool of Psychological Sciences, Tel Aviv University, Tel Aviv, Israel.
Yossi Levi-BelzThe Lior Tsfaty Center for Suicide and Mental Pain Studies, University of Haifa, Israel.
Ido LurieShalvata Mental Health Center, Hod Hasharon, Israel; School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Milton L WainbergNew York State Psychiatric Institute and Department of Psychiatry, New York, NY, United States of America; Columbia University Vagelos College of Physicians & Surgeons, New York, NY, United States of America.
Shlomo MendlovicShalvata Mental Health Center, Hod Hasharon, Israel; School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Yuval NeriaNew York State Psychiatric Institute and Department of Psychiatry, New York, NY, United States of America; Columbia University Vagelos College of Physicians & Surgeons, New York, NY, United States of America.
Doron AmsalemNew York State Psychiatric Institute and Department of Psychiatry, New York, NY, United States of America; Columbia University Vagelos College of Physicians & Surgeons, New York, NY, United States of America.

Funding

Global Mental Health Research Fellowship: Interventions That Make a DifferenceT32MH096724 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MILTON L WAINBERG · 2012 to 2026
$4.4M
NIMH NIH HHS T32 MH096724
6 · The paper itself

Abstract

backgroundOngoing armed conflicts expose civilian populations to sustained psychological trauma. While PTSD and depression are well documented, evidence suggests that civilians may also experience moral injury, particularly through a sense of potential moral injuries, events of betrayal (PMIE-Betrayal) by leaders or institutions. This betrayal can manifest as feelings of abandonment, unfulfilled promises of safety, or perceived neglect. Despite known links to distress, betrayal's evolving relationship with PTSD and depression during ongoing trauma is less known.

methods685 adults residing in conflict-affected areas in Israel, completed assessments at three time points in three months (baseline, 30-day, and 90-day assessments), reporting PTSD symptoms, depressive symptoms, betrayal-related moral injury, and war-related stressors. Structural equation modeling and multi-group analyses examined reciprocal (bi-directional) associations, comparing individuals with higher versus lower levels of war-related trauma exposure.

resultsHigh rates of PTSD (16-17%), depression (9-11%), and comorbid PTSD-depression (20-24%) persisted across time. Longitudinal cross-lagged analysis revealed novel bi-directional associations between PTSD and depression, with a sense of betrayal predicting later symptom severity and being shaped by earlier distress. Among highly exposed individuals, betrayal was more strongly linked to PTSD, while among those with lower exposure, it was more closely related to depression.

conclusionsBetrayal plays a central role in the development and maintenance of PTSD and depression, acting as both a consequence and a driver of psychological distress. A heightened sensitivity to perceived betrayal may increase vulnerability for potentially morally injurious experiences (PMIEs), reinforcing the need for trauma-informed care that addresses moral injury and institutional trust in civilian populations facing ongoing threats.

Indexed as

DepressionStress Disorders, Post-TraumaticTrustAdultFemaleHumansIsraelLongitudinal StudiesMaleMiddle AgedCiviliansDepressionLongitudinal studyMoral injury – BetrayalOngoing conflictPTSDWar trauma

Identifiers

PMID41921878
PMCPMC13213874

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.