ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2026
Intrinsic Diversity in Odor-Evoked Calcium Rises across
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Across species, olfactory receptor neurons (ORNs) exhibit stimulus-driven changes in gene expression, with calcium as a key activity signal. However, it remains unclear whether neuronal activity elevates intracellular calcium with differential gain across ORN types, which could then disparately influence a neuron's propensity for activity-dependent modulation. To address this possibility, we combined simultaneous electrophysiology and calcium imaging to systematically map odor-evoked calcium gain across the majority of characterized
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