Evidence map›Paper›PMID 41923288›Full record

ArticleNeurogastroenterology and motility2026

Avoidant-Restrictive Food Intake Disorder Is Common in Adults With Cyclic Vomiting Syndrome and Is Associated With Malnutrition.

Thangam Venkatesan, Praveen S Goday, Saranya Arumugam, Kebire Gofar, Mahima Vyas, Ana Petrova, Raul Jimenez-Castillo, Muhammad Ayyan, Sonali Srivastava, Kristen Heitman and 3 more

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In one paragraph

Article in Neurogastroenterology and motility, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Thangam VenkatesanDivision of Gastroenterology, Hepatology and Nutrition, The Ohio State University, Columbus, Ohio, USA.
Praveen S GodayDivision of Pediatric Gastroenterology and Nutrition, Nationwide Children's Hospital, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0001-6714-5173
Saranya ArumugamDivision of Gastroenterology, Hepatology and Nutrition, The Ohio State University, Columbus, Ohio, USA.
Kebire GofarDivision of Gastroenterology, Hepatology and Nutrition, The Ohio State University, Columbus, Ohio, USA.
Mahima VyasDivision of Gastroenterology, Hepatology and Nutrition, The Ohio State University, Columbus, Ohio, USA.
Ana PetrovaDivision of Gastroenterology, Hepatology and Nutrition, The Ohio State University, Columbus, Ohio, USA.
Raul Jimenez-CastilloDivision of Pediatric Gastroenterology and Nutrition, Nationwide Children's Hospital, Columbus, Ohio, USA.
Muhammad AyyanDivision of Gastroenterology, Hepatology and Nutrition, The Ohio State University, Columbus, Ohio, USA.
Sonali SrivastavaDivision of Gastroenterology, Hepatology and Nutrition, The Ohio State University, Columbus, Ohio, USA.
Kristen HeitmanSchool of Health and Rehabilitation Sciences, Health Sciences, The Ohio State University, Columbus, Ohio, USA.
Peter MadrilSchool of Health and Rehabilitation Sciences, Health Sciences, The Ohio State University, Columbus, Ohio, USA.
Kristin GoheenSchool of Health and Rehabilitation Sciences, Health Sciences, The Ohio State University, Columbus, Ohio, USA.
Kristen M RobertsSchool of Health and Rehabilitation Sciences, Medical Dietetics, The Ohio State University, Columbus, Ohio, USA.

Funding

Boone Family Foundation
6 · The paper itself

Abstract

backgroundIn cyclic vomiting syndrome (CVS), approximately 30% of patients remain symptomatic between episodes. We hypothesized that avoidance of presumed food triggers contributes to avoidant/restrictive food intake disorder (ARFID) and is associated with nutritional consequences in adults with CVS.

methodsWe prospectively studied adults diagnosed with CVS who completed the Nine-Item ARFID Screen (NIAS), Eating Disorder Questionnaire (EDE-QS), Food Security Questionnaire, and the VioScreen food frequency questionnaire. Nutrition status was assessed by a registered dietitian nutritionist (RDN). KEY

resultsAmong 80 participants (mean age 39 ± 16 years; 77.5% female), 30 (37.5%) screened positive for ARFID risk (NIAS+). Eight patients (10%) screened positive for eating disorder risk as well and were excluded from analyses. Those at risk for ARFID (NIAS+) were younger (32 ± 11 vs. 46 ± 16 y), had moderate-severe CVS (90% vs. 10%), anxiety (67% vs. 38%), depression (66% vs. 33%), reported more inter-episodic symptoms, and used cannabis more often (50% vs. 30%) (all p < 0.05), though cannabis-use disorder was not higher in this group. Those at risk for ARFID were more likely to be malnourished (73% vs. 30%) and at risk for food insecurity (30% vs. 0%) (both p < 0.001). These participants also consumed fewer calories and had several micronutrient intakes below recommendations. CONCLUSIONS AND INFERENCES: About a third of patients with CVS screened positive for ARFID. This was associated with malnutrition and deficient intake of several micronutrients. Screening for ARFID, disordered eating, and food insecurity is warranted. RDN involvement in developing targeted interventions may impact nutritional outcomes.

Indexed as

Avoidant Restrictive Food Intake DisorderMalnutritionVomitingAdultFemaleHumansMaleMiddle AgedNutritional StatusProspective StudiesYoung Adultavoidant food restrictioncyclic vomitingdisorders of gut brain interactionnutrition

Identifiers

PMID41923288
PMCPMC13044328

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.