Evidence mapPaperPMID 41923784Full record

ArticleArchives of clinical and medical case reports2026

A Comprehensive Analysis of Dermatological Manifestations in Lower Limb Para-Athletes.

Andre Aabedi, Vera Wang, Devendra K Agrawal

Erratum issuedAbstract read
In one paragraph

Article in Archives of clinical and medical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Andre AabediDepartment of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California 91766, USA.
Vera WangDepartment of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California 91766, USA.
Devendra K AgrawalDepartment of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California 91766, USA.

Funding

Research Education Program to Promote Diversity in Immunologic and Allergic DiseasesR25AI179582 · WESTERN UNIVERSITY OF HEALTH SCIENCES · 2025 to 2025
$379k
NIAID NIH HHS R25 AI179582
6 · The paper itself

Abstract

In this article, a critical evaluation of current evidence is presented on the prevalence, mechanisms, prevention, and management of sport-related skin complications in amputee athletes using lower limb prostheses, highlighting emerging technologies aimed at improving skin health and athletic performance. Skin complications were highly prevalent, affecting 34%-77% of lower limb prosthesis users, with even greater frequency among athletes. The most common conditions included maceration, friction blisters, pressure ulcers, contact dermatitis, verrucous and epidermal hyperplasia, and bacterial or fungal infections. Key risk factors encompassed poor prosthetic fit, elevated activity levels, increased perspiration, prolonged wear, inadequate hygiene, and hot or humid environments. Mechanical loading and shear stress at the socket-skin interface, compounded by moisture and heat retention, were central pathophysiologic drivers. Prevention and management strategies emphasize meticulous prosthetic fitting, consistent hygiene practices, routine skin inspection, and prompt intervention for early lesions. Multidisciplinary collaboration among dermatologists, prosthetists, and rehabilitation specialists improves detection and management outcomes. Recent innovations including vented liners, temperature-regulating materials, antimicrobial coatings, and sensor-based "smart prosthetics" show promise in reducing friction, heat, and infection risk, though evidence in athletic populations remains limited. Cutaneous complications in amputee athletes are common, multifactorial, and preventable. Optimal prosthetic fit, athlete education, and coordinated interdisciplinary care are essential for minimizing morbidity and maintaining athletic participation. Technological advancements such as real-time pressure and temperature monitoring, antimicrobial materials, and adaptive socket systems may transform prevention strategies, but further sport-specific, longitudinal research is required to validate their clinical impact and guide evidence-based practice.

Indexed as

DermatitisFriction and shear forcesLower limb amputeesPressure ulcersProsthetic skin complicationsProsthetic socket interface

Identifiers

PMID41923784
PMCPMC13038035

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.