Evidence map›Paper›PMID 41924306›Full record

ArticleGut microbes reports2026

Oleoylethanolamide supplementation enriches Akkermansia muciniphila and modulates intestinal barrier function in adults with obesity: A randomized, double-blind, placebo-controlled trial.

Romeo Batacan, Amanda Rao, Yadav Sharma Bajagai, Dragana Stanley, David Briskey

Abstract read
In one paragraph

Article in Gut microbes reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Romeo BatacanSchool of Health, Medical and Applied Sciences, Central Queensland University, Rockhampton, Australia.
Amanda RaoRDC Clinical, Brisbane, Australia.
Yadav Sharma BajagaiSchool of Health, Medical and Applied Sciences, Central Queensland University, Rockhampton, Australia.
Dragana StanleySchool of Health, Medical and Applied Sciences, Central Queensland University, Rockhampton, Australia.
David BriskeyRDC Clinical, Brisbane, Australia.ORCID https://orcid.org/0000-0001-9867-6700

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Targeted modulation of the gut microbiome represents a promising nutritional strategy to support metabolic and intestinal health in overweight and obese adults. Oleoylethanolamide (OEA) is an endogenous lipid mediator that regulates satiety, lipid metabolism, and inflammation, but its effects on the human microbiome are not well defined. In this randomized, double-blind, placebo-controlled trial, 57 adults with obesity (BMI 30-40 kg/m²) received either 300 mg of TRPTI, providing 250 mg/day of OEA (

Indexed as

Akkermansia muciniphilafaecalibacterium prausnitziigut microbiomeintestinal barrieroccludinOleoylethanolamide

Identifiers

PMID41924306
PMCPMC13037523

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.