ArticleCureus2026
Influence of the Postovulatory Progesterone on the Outcome of In Vitro Fertilization.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate the influence of postovulatory progesterone (P4) on the outcome of in vitro fertilization (IVF). MATERIALS AND
methodsThis was a prospective cohort study which included 400 patients (300 in the control group and 100 in the group with elevated preovulatory P4 (preovulatory P4 > 4.77 nmol/L) - 85 normal responders and 15 high responders). The influence of postovulatory P4 on the IVF outcome has been investigated in this study.
resultsIt was found that the P4 value on the fifth cycle day at a concentration ≤425.7 nmol/L has a high sensitivity (86.21%, 95% CI 81.7-90.0%) and a low specificity (23.64%, 95% CI 16.1-32.7%) in all patients in the study. The obtained results showed that P4 values on day 5 >425,7 nmol/L in all patients, and the P4 on the 5th day >384,6 nmol/L among patients with elevated preovulatory P4 represent a threshold for the successful IVF procedure (positive ultrasound visualization of the gestational sac at six weeks of pregnancy with the presence of fetal heart action after embryo transfer).
conclusionThe P4 on the fifth day >425,7 nmol/L could be a potential marker for the success of the IVF procedures among all the patients, and with P4 on the fifth day >384,6 nmol/L among patients with elevated preovulatory P4.
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