Evidence mapPaperPMID 41924740Full record

ReviewFrontiers in medicine2026

Comprehensive management of ischemic stroke with traditional Chinese medicine: a new exploration.

Qianshi Zhang, Xu Dong, Hong Huo, Ying Zhang, Mengyun Zhang, Dongyan Wang

Abstract readReview
In one paragraph

Review in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qianshi ZhangDepartment of Graduate School, Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.
Xu DongThird Ward of Acupuncture and Moxibustion Department, The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.
Hong HuoThird Ward of Acupuncture and Moxibustion Department, The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.
Ying ZhangThird Ward of Acupuncture and Moxibustion Department, The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.
Mengyun ZhangDepartment of Graduate School, Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.
Dongyan WangThird Ward of Acupuncture and Moxibustion Department, The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ischemic stroke exhibits considerable variability across regions, age groups, sexes, and ethnicities, with risk factors encompassing genetic, environmental, and socioeconomic dimensions. Its pathophysiology is multifaceted and involves disturbances in energy metabolism, disruption of the BBB, and inflammatory processes, among other mechanisms. Diagnostic advancements including imaging modalities, biomarker identification, and artificial intelligence applications have significantly enhanced clinical practice. Therapeutic strategies primarily focus on reperfusion and antiplatelet therapies, while traditional Chinese medicine (TCM) demonstrates potential through multi-targeted and multi-modal approaches. Rehabilitation and prevention efforts underscore the importance of multidisciplinary collaboration, personalized treatment plans, and early risk factor interventions. Rooted in the traditional conceptualization of stroke, TCM exerts its effects via anti-inflammatory, antioxidant, and metabolic regulatory pathways, and has shown promising clinical outcomes when integrated with conventional medicine. Nonetheless, challenges remain regarding the robustness of the efficacy evidence, standardization of syndrome differentiation, and safety concerns. Future directions point toward the integration of multi-omics technologies, artificial intelligence, precision medicine, and international collaboration to advance the comprehensive management of ischemic stroke by incorporating TCM.

Indexed as

diagnosis and treatmentintegrative medicine (TCM + modern medicine)ischemic strokepathological mechanismrehabilitation and preventionTCM

Identifiers

PMID41924740
PMCPMC13036231

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.