Evidence map›Paper›PMID 41925110›Full record

ArticleAnnals of neurology2026

Network Colocalization Correlates of Depression and Anxiety in Pediatric Focal Cortical Dysplasia-Related Epilepsy.

Xiaotong Li, Ty Charde, Venkata Sita Priyanka Illapani, Sonya M Leikin, Hua Xie, Chima O Oluigbo, L Gilbert Vezina, William D Gaillard, Hayley J Loblein, Perrine Heymann and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Xiaotong LiCenter for Neuroscience Research, Children's National Hospital, The George Washington University School of Medicine, Washington, DC.
Ty ChardeCenter for Neuroscience Research, Children's National Hospital, The George Washington University School of Medicine, Washington, DC.
Venkata Sita Priyanka IllapaniCenter for Neuroscience Research, Children's National Hospital, The George Washington University School of Medicine, Washington, DC.
Sonya M LeikinCenter for Neuroscience Research, Children's National Hospital, The George Washington University School of Medicine, Washington, DC.
Hua XieCenter for Neuroscience Research, Children's National Hospital, The George Washington University School of Medicine, Washington, DC.
Chima O OluigboCenter for Neuroscience Research, Children's National Hospital, The George Washington University School of Medicine, Washington, DC.
L Gilbert VezinaCenter for Neuroscience Research, Children's National Hospital, The George Washington University School of Medicine, Washington, DC.
William D GaillardCenter for Neuroscience Research, Children's National Hospital, The George Washington University School of Medicine, Washington, DC.
Hayley J LobleinCenter for Neuroscience Research, Children's National Hospital, The George Washington University School of Medicine, Washington, DC.
Perrine HeymannCenter for Neuroscience Research, Children's National Hospital, The George Washington University School of Medicine, Washington, DC.
Leigh N SepetaCenter for Neuroscience Research, Children's National Hospital, The George Washington University School of Medicine, Washington, DC.
Madison M BerlCenter for Neuroscience Research, Children's National Hospital, The George Washington University School of Medicine, Washington, DC.ORCID 0000-0002-2469-1518
Adelaide S RobbCenter for Neuroscience Research, Children's National Hospital, The George Washington University School of Medicine, Washington, DC.
Nathan T CohenCenter for Neuroscience Research, Children's National Hospital, The George Washington University School of Medicine, Washington, DC.ORCID 0000-0002-1410-3487

Funding

Neurobehavioral Evaluation CoreP50HD105328 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI WILLIAM Davis GAILLARD · 2021 to 2026
$9.3M
Determining network signatures of pharmacoresistance in focal cortical dysplasia-related epilepsyK23NS131522 · NINDS · CHILDREN'S RESEARCH INSTITUTE · PI Nathan Tyler Cohen · 2025 to 2026
$431k
NICHD NIH HHS P50 HD105328NINDS NIH HHS K23 NS131522
6 · The paper itself

Abstract

objectiveFocal cortical dysplasia (FCD) is the most common cause of surgically treatable, drug-resistant epilepsy in children. Anxiety and depression are frequent comorbidities in epilepsy. This study examined whether FCD overlap with large-scale functional networks, the default mode network (DMN) and the limbic network, is associated with parent-reported anxiety or depressive symptoms.

methodsSixty-nine patients with FCD-related epilepsy completed the Child Behavior Checklist (CBCL), among whom 56 finished the 6 to 18 years version of CBCL (CBCL

resultsFifty-six patients had preoperative CBCL

interpretationFCD

Indexed as

AnxietyDefault Mode NetworkDepressionEpilepsyFocal Cortical DysplasiaNerve NetAdolescentChildFemaleHumansMagnetic Resonance ImagingMale

Identifiers

PMID41925110
PMCPMC13244361

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.