Evidence map›Paper›PMID 41925307›Full record

ArticleJournal of clinical microbiology2026

Development and evaluation of dried urine strip for genital chlamydia and gonorrhea testing.

Suzanne Gibbons, Clarissa Klenke, Felicia Roy, Vanessa Schulz, Kimberly Ta, Sharon Simon, Jennifer Beirnes, Sabaparvin Shaikh, Ravinder Lidder, Christine Mesa and 11 more

Abstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Suzanne GibbonsNational Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
Clarissa KlenkeNational Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
Felicia RoyNational Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.ORCID 0009-0000-2568-6721
Vanessa SchulzNational Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
Kimberly TaNational Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
Sharon SimonNational Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
Jennifer BeirnesNational Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
Sabaparvin ShaikhNational Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
Ravinder LidderNational Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
Christine MesaNational Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
Shelley PetersonNational Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.ORCID 0000-0002-6432-9257
Virginia ReshBCCDC Public Health Laboratory, BC Centre for Disease Control, Vancouver, British Columbia, Canada.
Janet FungBCCDC Public Health Laboratory, BC Centre for Disease Control, Vancouver, British Columbia, Canada.
Jennifer GrantBCCDC Public Health Laboratory, BC Centre for Disease Control, Vancouver, British Columbia, Canada.
Olivia GemmellHQ Toronto, Toronto, Ontario, Canada.
Kevin WoodwardHQ Toronto, Toronto, Ontario, Canada.
Paul SandstromNational Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
Alberto SeveriniDepartment of Medical Microbiology and Infectious Diseases, Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Irene MartinNational Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.ORCID 0000-0002-3941-5583
John KimNational Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
Aida SivroNational Microbiology Laboratory Branch, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.ORCID 0000-0001-9215-5285

Funding

Public Health Agency of Canada
6 · The paper itself

Abstract

Here, we developed and evaluated a filter-paper urine collection method for chlamydia and gonorrhea testing. Dried urine strips (DUS) were developed to fit into the sample collection tube used for high throughput Hologic Aptima Combo 2 assay, minimizing processing post-sample collection. IMPORTANCE: Innovative sampling methods that are convenient, accurate, and user-friendly are crucial to increase sexually transmitted infection (STI) testing uptake. This study establishes a novel dried urine strip sample collection method for chlamydia and gonorrhea testing and downstream molecular characterization. Results show no inferiority of dried urine strips compared to urine, with regard to diagnostic performance, when analyzed using molecular in-house and commercial assays for chlamydia and gonorrhea detection. A dried urine strip sample collection method for chlamydia and gonorrhea testing offers significant advantages in resource-limited or stigmatized settings; it enables self-collection, mail-in return, and long-term storage at ambient temperatures, making it ideal for reaching underserved populations. The broader public health impact is the expansion of STI screening access and reduction in STI transmission by offering a discreet, scalable alternative to traditional specimen collection.

Indexed as

Chlamydia InfectionsChlamydia trachomatisGonorrheaSpecimen HandlingUrineUrine Specimen CollectionDesiccationFemaleHumansNeisseria gonorrhoeaeSensitivity and SpecificityTemperatureantimicrobial resistancechlamydiadried urinefilter papergenotypinggonorrheaSTI testing

Identifiers

PMID41925307
PMCPMC13170174

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.