Evidence map›Paper›PMID 41925947›Full record

ReviewHuman cell2026

Advancing diagnostic biomarkers in Alzheimer's disease: interdisciplinary innovations and technological frontiers.

Faheem Patwekar, Mohsina Patwekar, Lee Seong Wei, Rohit Sharma, Ryan Varghese, Arifullah Mohammed

Abstract readReview
PubMed Publisher
In one paragraph

Review in Human cell, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Faheem PatwekarDepartment of Agriculture Science, Faculty of Agro-Based Industry, Universiti Malaysia Kelantan, 17600, Jeli, Kelantan, Malaysia. ifaheemp@gmail.com.ORCID https://orcid.org/0000-0003-0453-8126
Mohsina PatwekarDepartment of Pharmacology, Luqman College of Pharmacy, PB 86, Old Jewargi Road, Gulbarga, Karnataka, India.ORCID https://orcid.org/0000-0002-5043-366X
Lee Seong WeiDepartment of Agriculture Science, Faculty of Agro-Based Industry, Universiti Malaysia Kelantan, 17600, Jeli, Kelantan, Malaysia. leeseong@umk.edu.my.
Rohit SharmaDepartment of Rasa Shastra and Bhaishajya Kalpana, Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, 221005, India. rohitsharma@bhu.ac.in.ORCID http://orcid.org/0000-0002-3682-3573
Ryan VargheseDepartment of Pharmaceutical Sciences, Philadelphia College of Pharmacy, Saint Joseph's University, Philadelphia, PA, 19104, USA.ORCID https://orcid.org/0000-0001-6817-2261
Arifullah MohammedDepartment of Biotechnology, KoneruLakshmaiah University (KLEF), Vaddeswaram Campus, Guntur, Andhra Pradesh, 522302, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Developing diagnostic biomarkers for Alzheimer's disease (AD) is at the cutting edge of interdisciplinary research and technical advancement. This comprehensive analysis investigates potential options for improving diagnostic accuracy and early detection of AD. Identifying biomarkers other than Aβ and tau proteins, such as synaptic dysfunction markers and metabolic indicators, is a novel technique. Integrating multi-omics data provides a comprehensive picture of AD pathophysiology, assisting in the discovery of biomarkers and treatment targets. Advances in technology, notably nanotechnology and biosensors, show promise for highly sensitive and specific platforms capable of identifying AD-related biomarkers in physiological fluids. AI and machine learning algorithms are critical in analyzing large datasets, improving pattern identification, and increasing diagnostic accuracy. Predictive models based on various biomarkers and clinical data open the way for personalized medicine methods in the treatment of AD. More advancements in PET and MRI tracers are required for targeted and sensitive imaging of specific AD-related clinical alterations. Wearing gadgets and seeing digital health signs have helped us to find diseases early and track them over time. They even allow monitoring from afar and all the time. This comprehensive review brings together new developments and teamwork across different fields. In this way, it guides to enhance how to identify AD. By mixing these new methods, we aim to change the diagnosis of AD early and accurately. This allows us to focus on treatments and push forward new cures for AD.

Indexed as

Alzheimer DiseaseBiomarkersInterdisciplinary ResearchArtificial IntelligenceBiosensing TechniquesDigital HealthEarly DiagnosisHumansMachine LearningMultiomicsNanotechnologyPrecision MedicineBiomarkersAlzheimer’s diseaseArtificial intelligenceBiomarkersDiagnosisMRIPersonalized medicine

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.