Evidence map›Paper›PMID 41927278›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2026

Detection of Focal Lesions in Epilepsy with [

Vanessa Pakula, Julia S Dorneich, Lukas Frontzkowski, Laura M Bartos, Nicholas Fearns, Sebastian N Roemer-Cassiano, Simon Lindner, Andreas Zwergal, Elisabeth Kaufmann, Günter Höglinger and 6 more

Abstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Vanessa PakulaDepartment of Nuclear Medicine, LMU University Hospital, Munich, Germany.
Julia S DorneichDepartment of Nuclear Medicine, LMU University Hospital, Munich, Germany.
Lukas FrontzkowskiDepartment of Nuclear Medicine, LMU University Hospital, Munich, Germany.
Laura M BartosDepartment of Nuclear Medicine, LMU University Hospital, Munich, Germany.
Nicholas FearnsDepartment of Neurology, LMU University Hospital, LMU Munich, Munich, Germany.
Sebastian N Roemer-CassianoInstitute for Stroke and Dementia Research, LMU Hospital, LMU Munich, Munich, Germany.
Simon LindnerDepartment of Nuclear Medicine, LMU University Hospital, Munich, Germany.
Andreas ZwergalDepartment of Neurology, LMU University Hospital, LMU Munich, Munich, Germany.
Elisabeth KaufmannDepartment of Neurology, LMU University Hospital, LMU Munich, Munich, Germany.
Günter HöglingerDepartment of Neurology, LMU University Hospital, LMU Munich, Munich, Germany.
Nicolai FranzmeierInstitute for Stroke and Dementia Research, LMU Hospital, LMU Munich, Munich, Germany.
Rudolf A WernerDepartment of Nuclear Medicine, LMU University Hospital, Munich, Germany.
Christian VollmarDepartment of Neurology, LMU University Hospital, LMU Munich, Munich, Germany.
Jan RémiDepartment of Neurology, LMU University Hospital, LMU Munich, Munich, Germany.
Matthias BrendelDepartment of Nuclear Medicine, LMU University Hospital, Munich, Germany.
Johannes GnörichDepartment of Nuclear Medicine, LMU University Hospital, Munich, Germany; johannes.gnoerich@med.uni-muenchen.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synaptic vesicle protein 2A (SV2A) is a universal marker of synaptic density. Recent advances in SV2A-targeted radiotracers have opened new windows into synaptic imaging. In focal epilepsy, synaptic dysfunction is a central pathologic feature. Unlike [

Indexed as

Epilepsies, PartialMembrane GlycoproteinsNerve Tissue ProteinsPositron-Emission TomographyAdolescentAdultFemaleFluorodeoxyglucose F18HumansMaleMiddle AgedPyridinesPyrrolidinonesYoung AdultFluorodeoxyglucose F18Membrane GlycoproteinsNerve Tissue ProteinsPyridinesPyrrolidinonesSV2A protein, humanUCB-H compound[18F]FDG PETfocal epilepsySV2A PETsynaptic density

Identifiers

PMID41927278
PMCPMC13224912

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.