Evidence map›Paper›PMID 41927744›Full record

ArticleCommunications chemistry2026

μ₃-Oxo nucleophile formation enables efficient S

Saki Maruoka, Yohei Kametani, Eisuke Magome, Hiroyuki Setoyama, Masahide Kawamoto, Masaki Horitani, Takamasa Teramoto, Yoshimitsu Kakuta, Yoshihito Shiota, Kazunari Yoshizawa and 1 more

Abstract read
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In one paragraph

Article in Communications chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Saki MaruokaLaboratory of Biophysical Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, Fukuoka, Japan.
Yohei KametaniInstitute for Materials Chemistry and Engineering and IRCCS, Kyushu University, Fukuoka, Japan.ORCID http://orcid.org/0000-0001-8923-9939
Eisuke MagomeSAGA Light Source, Tosu, Japan.ORCID http://orcid.org/0000-0001-9410-1897
Hiroyuki SetoyamaSAGA Light Source, Tosu, Japan.
Masahide KawamotoSAGA Light Source, Tosu, Japan.ORCID http://orcid.org/0009-0000-4666-5620
Masaki HoritaniDepartment of Applied Biochemistry and Food Science, Saga University, Saga, Japan.ORCID http://orcid.org/0000-0002-8881-0600
Takamasa TeramotoLaboratory of Biophysical Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, Fukuoka, Japan.ORCID http://orcid.org/0000-0003-1555-5394
Yoshimitsu KakutaLaboratory of Biophysical Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, Fukuoka, Japan.ORCID http://orcid.org/0000-0002-0781-2074
Yoshihito ShiotaInstitute for Materials Chemistry and Engineering and IRCCS, Kyushu University, Fukuoka, Japan.ORCID http://orcid.org/0000-0003-2054-9845
Kazunari YoshizawaInstitute for Materials Chemistry and Engineering and IRCCS, Kyushu University, Fukuoka, Japan.ORCID http://orcid.org/0000-0002-6279-9722
Keiichi WatanabeDepartment of Applied Biochemistry and Food Science, Saga University, Saga, Japan. watakei@knwu.ac.jp.ORCID http://orcid.org/0000-0003-4704-9568

Funding

MEXT | Japan Society for the Promotion of Science (JSPS) JP23K26836MEXT | Japan Society for the Promotion of Science (JSPS) JP23KJ1741MEXT | Japan Society for the Promotion of Science (JSPS) JP24K21245MEXT | Japan Society for the Promotion of Science (JSPS) JP25K08678
6 · The paper itself

Abstract

Inorganic pyrophosphatases are essential metalloenzymes for phosphate metabolism. Bacterial Family II Inorganic pyrophosphatases utilize a trinuclear metal center and exhibit higher catalytic activity than binuclear counterparts. Here we show the mechanism underlying this enhanced hydrolytic efficiency in the enzyme from Shewanella sp. AS-11 using X-ray absorption spectroscopy, site-directed mutagenesis, and density functional theory calculations. We identify a catalytic μ

Identifiers

PMID41927744
PMCPMC13219714

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.