Evidence map›Paper›PMID 41928518›Full record

ArticleImmunity2026

Distinct tissue niches contribute to prostate tissue-resident memory CD8

Kennidy K Takehara, Alexander Monell, Vida Luna, Baxter Melisso, Kianoosh M Mempel, Kitty P Cheung, Natalie Zane, Peter P Challita, Amir Ferry, Ethan C Xu and 15 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Immunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Kennidy K TakeharaSchool of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA 92093, USA; Allen Institute for Immunology, Seattle, WA 98109, USA.
Alexander MonellSchool of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA 92093, USA.
Vida LunaLa Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Baxter MelissoSchool of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA 92093, USA.
Kianoosh M MempelSchool of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA 92093, USA.
Kitty P CheungSchool of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA 92093, USA.
Natalie ZaneSchool of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA 92093, USA.
Peter P ChallitaSchool of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA 92093, USA.
Amir FerrySchool of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA 92093, USA.
Ethan C XuLa Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Violante OlivariLa Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Nicole E ScharpingSchool of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA 92093, USA.
Giovanni GallettiSchool of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA 92093, USA.
Sara QuonSchool of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA 92093, USA.
Julien R IshibashiAllen Institute for Immunology, Seattle, WA 98109, USA.
Nina EstepAllen Institute for Immunology, Seattle, WA 98109, USA.
John B JohannesonAllen Institute for Immunology, Seattle, WA 98109, USA.
Chinmayi PandyaDepartment of Medicine and Urology, Moores Cancer Center, University of California, San Diego, La Jolla, CA 92037, USA.
Stephanie D Anover-SombkeAllen Institute for Immunology, Seattle, WA 98109, USA.
Rana R McKayDepartment of Medicine and Urology, Moores Cancer Center, University of California, San Diego, La Jolla, CA 92037, USA.
Peter J SkeneAllen Institute for Immunology, Seattle, WA 98109, USA.
Matthew E PipkinThe Hebert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, FL 33548, USA.
Maximilian HeegSchool of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA 92093, USA; Allen Institute for Immunology, Seattle, WA 98109, USA.
Miguel Reina-CamposSchool of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA 92093, USA; La Jolla Institute for Immunology, La Jolla, CA 92037, USA. Electronic address: miguel@lji.org.
Ananda W GoldrathSchool of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA 92093, USA; Allen Institute for Immunology, Seattle, WA 98109, USA. Electronic address: agoldrath@ucsd.edu.

Funding

Transcription factor regulation of CD4 and CD8 T cell effector and memory differentiation and functionP01AI145815 · NIAID · UNIVERSITY OF FLORIDA · PI PIPKIN, MATTHEW EUGENE · 2020 to 2024
$11.0M
Regulation of T cell immunity to viral infectionR01AI072117 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GOLDRATH, ANANDA W · 2008 to 2022
$5.4M
Systems-level identification of key regulators deciding immune cell stateR01AI150282 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WANG, WEI · 2020 to 2024
$3.5M
T cell maintenance: molecular mediators of T cell differentiation and survivalR37AI067545 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ananda W Goldrath · 2022 to 2026
$3.0M
Tissue-specific adaptions to promote localized T cell memoryR01AI179952 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ananda W Goldrath · 2024 to 2026
$1.8M
Tumor-infiltrating T cell metabolic dysfunction and genetic reprogramming for effective immunotherapyK00CA222711 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SCHARPING, NICOLE E · 2020 to 2023
$360k
Understanding Prostate Resident Memory T CellsF31AI176705 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TAKEHARA, KENNIDY · 2024 to 2025
$64k
NCI NIH HHS K00 CA222711NIAID NIH HHS F31 AI176705NIAID NIH HHS P01 AI145815NIAID NIH HHS R01 AI072117NIAID NIH HHS R01 AI150282NIAID NIH HHS R01 AI179952NIAID NIH HHS R37 AI067545
6 · The paper itself

Abstract

The prostate is an important exocrine organ, a barrier tissue of the male reproductive system, and a common site of malignancy, yet CD8

Indexed as

CD8-Positive T-LymphocytesCell DifferentiationImmunologic MemoryMemory T CellsProstateAnimalsHumansInterleukin-15Interleukin-7MaleMiceMice, Inbred C57BLSignal TransductionTransforming Growth Factor betaInterleukin-15Interleukin-7Transforming Growth Factor betaCD8 T cellmemory T cellprostatespatial transcriptomicstissue-resident memory T cells

Identifiers

PMID41928518
PMCPMC13577651

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.