Evidence mapPaperPMID 41928875Full record

ReviewFrontiers in endocrinology2026

Artificial intelligence-driven assessment of sarcopenia in orthopedic geriatrics: technical progress and clinical implications.

Tengbo Pei, Yutian Lei, Yufang Gao, Minjie Zhang, Tao Xu, Weina Yang, Qifu Wen, Qiang Liu

Abstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tengbo PeiDepartment of Medical Laboratory, Xianyang Central Hospital, Xianyang, Shaanxi, China.
Yutian LeiDepartment of Orthopedics I, Xi'an Daxing Hospital, Xi'an, Shaanxi, China.
Yufang GaoDepartment of Medical Laboratory, Xianyang Central Hospital, Xianyang, Shaanxi, China.
Minjie ZhangDepartment of Medical Laboratory, Xianyang Central Hospital, Xianyang, Shaanxi, China.
Tao XuDepartment of Medical Laboratory, Xianyang Central Hospital, Xianyang, Shaanxi, China.
Weina YangDepartment of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Qifu WenDepartment of Medical Laboratory, Xianyang Central Hospital, Xianyang, Shaanxi, China.
Qiang LiuDepartment of Orthopedics, Xianyang Central Hospital, Xianyang, Shaanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarcopenia, a progressive skeletal muscle disorder characterized by the loss of muscle mass and function, represents a significant challenge in geriatric orthopedics, with prevalence reaching as high as 48.7% in surgical populations. It is strongly associated with increased risks of falls, secondary fractures, postoperative complications, and mortality. Despite its clinical importance, traditional diagnostic methods like Dual-energy X-ray Absorptiometry (DXA) and Bioelectrical Impedance Analysis (BIA) are often impractical in acute orthopedic settings due to patient immobilization, positioning constraints, and postoperative fluid imbalances. This narrative review aims to summarize how the emergence of artificial intelligence (AI), particularly deep learning, addresses these gaps by enabling automated, high-throughput opportunistic screening from routine clinical imaging. Convolutional neural networks achieve expert-level segmentation of muscle quantity and quality, with Dice similarity coefficients often exceeding 0.94. AI-derived metrics serve as robust independent predictors for adverse surgical outcomes, including prolonged length of stay and infection, as well as functional recovery and one-year mortality. By integrating these metrics into Clinical Decision Support Systems (CDSS) and Electronic Medical Records (EMR), AI facilitates a paradigm shift from reactive fracture management to proactive prevention through automated "zero-click" alerts and multidisciplinary intervention pathways. While significant challenges regarding technical standardization, biological variability, and model interpretability persist, AI-driven assessment is transforming geriatric orthopedic care from subjective evaluation toward precise, objective quantification.

Indexed as

Artificial IntelligenceGeriatricsOrthopedicsSarcopeniaDeep LearningHumansIntelligent SystemsSoft Computingartificial intelligenceclinical decision support systemsdeep learninggeriatric orthopedicsopportunistic screeningosteosarcopeniasarcopenia

Identifiers

PMID41928875
PMCPMC13038567

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.