Evidence map›Paper›PMID 41929451›Full record

ArticleFrontiers in cellular and infection microbiology2026

Structural analysis of ITS 1 gene of

Mehmet Murat Yasar, Ekrem Yasar, Nuri Yorulmaz, Gulcan Gurses, Habip Celik, Murat Guney, Ahmet Tas, Zubeyde Tanriverdi, Nebiye Yentur Doni

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Valorization ofCells · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mehmet Murat YasarVocational School of Health Services, Harran University, Sanliurfa, Türkiye.
Ekrem YasarDepartment of Biophysics, Faculty of Medicine, Erzincan Binali Yildirim University, Erzincan, Türkiye.
Nuri YorulmazPhysics Department, Faculty of Arts and Sciences, Harran University, Sanliurfa, Türkiye.
Gulcan GursesVocational School of Health Services, Harran University, Sanliurfa, Türkiye.
Habip CelikDepartment of Chemistry, Faculty of Science and Art, Agri Ibrahim Cecen University, Agri, Türkiye.
Murat GuneyDepartment of Chemistry, Faculty of Science and Art, Agri Ibrahim Cecen University, Agri, Türkiye.
Ahmet TasVocational School of Health Services, Harran University, Sanliurfa, Türkiye.
Zubeyde TanriverdiDepartment of Pharmaceutical Toxicology, Faculty of Pharmacy, Agri Ibrahim Cecen University, Agri, Türkiye.
Nebiye Yentur DoniDepartment of Clinical Microbiology, Faculty of Medicine, Harran University, Sanliurfa, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Leishmaniasis, a prevalent tropical disease caused by intracellular protozoa of the genus Methods: We identified and docked the ligand benzo[d][1,3]dioxol-5-yl 4-acetamidobenzenesulfonate (3) and synthesized the reaction of sesamol (1) with sulfonyl chloride (2), and the NMR and IR spectra were used for characterization, a potential inhibitor of this protein, followed by a 300-ns simulation using the GROMACS software. Results: The results showed that the protein structure in the ITS1 gene region of Conclusion: However, experimental studies are required to conclusively confirm its inhibitory efficacy. This study provides valuable insights for the development of new therapeutic approaches against leishmaniasis.

Indexed as

Antiprotozoal AgentsBenzodioxolesLeishmania tropicaProtozoan ProteinsLigandsModels, MolecularMolecular Docking SimulationMolecular Dynamics SimulationProtein BindingAntiprotozoal AgentsBenzodioxolesLigandsProtozoan Proteinsanti-leishmanial drugbenzo[d][1,3]dioxol-5-yl 4-acetamidobenzenesulfonateleishmaniasisL. tropicamolecular dockingmolecular dynamics simulation

Identifiers

PMID41929451
PMCPMC13040372

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.