Evidence mapPaperPMID 41929649Full record

ReviewInternational journal of nanomedicine2026

Nanoparticle-Based Targeted Drug Delivery Systems for Allergic Rhinitis: A Comprehensive Review.

Yuenan Wang, Yang Zhou, Boshen Liang, Shuoming Li, Zhenning Wang, Xiaodong Yan, Yiqing Gao, Tiangang Li, Qiong Qin, Shaoli Yang and 2 more

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yuenan Wang *Basic Medical College, Yunnan University of Chinese Medicine, Kunming, Yunnan, People's Republic of China.
Yang Zhou *First Clinical Medical College, Yunnan University of Chinese Medicine, Kunming, Yunnan, People's Republic of China.
Boshen Liang *School of Public Health and Management, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, People's Republic of China.
Shuoming LiBasic Medical College, Yunnan University of Chinese Medicine, Kunming, Yunnan, People's Republic of China.
Zhenning WangBasic Medical College, Yunnan University of Chinese Medicine, Kunming, Yunnan, People's Republic of China.
Xiaodong YanInstitute of Clinical Pharmacology, Nanchang University, Nanchang, Jiangxi, People's Republic of China.
Yiqing GaoBasic Medical College, Yunnan University of Chinese Medicine, Kunming, Yunnan, People's Republic of China.
Tiangang LiBasic Medical College, Yunnan University of Chinese Medicine, Kunming, Yunnan, People's Republic of China.
Qiong QinDepartment of Otolaryngology, The First Affiliated Hospital of Yunnan University of Chinese Medicine, Kunming, Yunnan, People's Republic of China.
Shaoli YangBasic Medical College, Yunnan University of Chinese Medicine, Kunming, Yunnan, People's Republic of China.
Fang GuoBasic Medical College, Yunnan University of Chinese Medicine, Kunming, Yunnan, People's Republic of China.
Jian NieBasic Medical College, Yunnan University of Chinese Medicine, Kunming, Yunnan, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allergic rhinitis (AR) is an immunoglobulin E (IgE)-mediated immune response triggered by inhaled allergens, primarily involving type 2 cell-driven nasal mucosal inflammation. Current clinical management of AR relies on pharmacotherapy and immunomodulatory therapies but is limited by treatment time windows, bioavailability, and side effects. Rational design of nanodrug carriers can enhance drug bioavailability and enable targeted delivery. Nanoparticles (NPs) transport drugs or gene fragments to nasal tissues via passive or active targeting, thereby improving therapeutic efficacy while minimizing damage to healthy tissues. This review summarizes recent applications of NPs in preclinical and clinical AR treatment, highlighting strategies for targeted therapy using nanodrugs. It discusses the benefits and mechanisms of innovative drug delivery systems in the treatment of AR and provides a comprehensive catalog of such systems. Finally, it outlines future prospects for improved clinical translation.

Indexed as

Anti-Allergic AgentsDrug Delivery SystemsNanoparticle Drug Delivery SystemNanoparticlesRhinitis, AllergicAnimalsHumansAnti-Allergic AgentsNanoparticle Drug Delivery Systemactive targetingAllergic rhinitisdrug delivery systemnanodrugnanoparticlespassive targetingtargeted therapy

Identifiers

PMID41929649
PMCPMC13039665

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.