Evidence map›Paper›PMID 41929926›Full record

ReviewJournal of anesthesia and translational medicine2025

Neuroprotective mechanisms of dexmedetomidine in perioperative neurocognitive disorders: From molecular pathways to clinical translation.

Zhi Shang, Yuyang Wu, Chen Gu, Ju Gao, Cunjin Wang

Abstract readReview
In one paragraph

Review in Journal of anesthesia and translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhi ShangClinical Medical College, Yangzhou University, Yangzhou 225001, China.
Yuyang WuClinical Medical College, Yangzhou University, Yangzhou 225001, China.
Chen GuClinical Medical College, Yangzhou University, Yangzhou 225001, China.
Ju GaoNorthern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou 225001, China.
Cunjin WangNorthern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou 225001, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Perioperative neurocognitive disorders (PNDs) are common severe complications observed in elderly patients following surgery, primarily characterized by a decline in postoperative cognitive function and memory. Dexmedetomidine, a highly selective α

Indexed as

Clinical translationDexmedetomidineMolecular pathwaysNeuroprotectionPerioperative neurocognitive disorders

Identifiers

PMID41929926
PMCPMC13001782

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.