Evidence map›Paper›PMID 41929936›Full record

ReviewInternational journal of women's health2026

Symptoms Experienced by Breast Cancer Patients Before, During and After Chemotherapy: A Systematic Review.

Yang Cao, Khuan Lee, Azlina Yusuf, Seong Ting Chen, Xue Dong, Lin Li, Poh Ying Lim

Abstract readReview
In one paragraph

Review in International journal of women's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yang CaoDepartment of Nursing, Faculty of Medicine & Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia.
Khuan LeeDepartment of Nursing, Faculty of Medicine & Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia.
Azlina YusufNursing Program, School of Health Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.
Seong Ting ChenDivision of Nutrition, Dietetics and Food Science, School of Health Sciences, IMU University, Bukit Jalil, Kuala Lumpur, Malaysia.
Xue DongDepartment of Nursing, Changchun University of Chinese Medicine, Changchun, Jilin, People's Republic of China.
Lin LiDepartment of Nursing, Faculty of Medicine & Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia.
Poh Ying LimDepartment of Community Health, Faculty of Medicine & Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia.ORCID 0000-0002-7765-4630

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Breast cancer is the most prevalent cancer among women worldwide. Chemotherapy remains a key element of treatment for a large proportion of breast cancer patients. Breast cancer patients undergoing chemotherapy often experience multiple symptoms that can impact their quality of life. This systematic review aimed to identify the symptoms experienced by breast cancer patients before, during and after chemotherapy treatment along with associated factors, to provide an evidence base for healthcare providers. Methods: Five electronic databases were searched from January 2015 to September 2025 encompassing observational studies. Two researchers independently screened the studies and extracted data. The Standard Quality Assessment Criteria for Evaluating Primary Research Papers was used to evaluate the quality of included studies. Results: Out of 5,588 records, 37 studies met the inclusion criteria. Majority of studies were conducted in Asia and the most common study type was cross-sectional studies (n=18, 48.6%). Anxiety, depression, chemotherapy-induced nausea and vomiting (CINV), fatigue and sleep problems were the most common symptoms observed in these studies. The factors reported were divided into non-modifiable factors (sociodemographic and disease related) and modifiable factors (physiological, psychological, lifestyle, nutritional and other related). Younger age was the most frequently reported risk factor for increased anxiety, depression, fatigue, nausea, and menopausal symptoms, followed by having children, greater number of chemotherapy cycles, higher BMI, lower performance status, and limited social support. Conclusion: Breast cancer patients undergoing chemotherapy experience a variety of symptoms. These findings underscore the importance of routine symptom screening and baseline risk assessment to enable early identification of high-risk patients and implementation of targeted interventions to optimize quality of life. Future research should prioritize identifying high-risk populations and implementing targeted early preventive interventions to enhance patient quality of life.

Indexed as

breast cancerchemotherapyrisk factorssymptomssystematic review

Identifiers

PMID41929936
PMCPMC13039652

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.