ArticleCureus2026
Atypical, Clinically Silent, Locally Advanced Pheochromocytoma Revealing Von Hippel-Lindau Type 2C Phenotype: A Case Report.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
6 authors.
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Abstract
Pheochromocytomas are rare neuroendocrine tumors arising from chromaffin cells of the adrenal medulla. Malignancy is defined by the presence of distant metastases. Approximately a substantial proportion are associated with germline mutations, particularly in the context of Von Hippel-Lindau (VHL) syndrome. We report the case of a 60-year-old man diagnosed with a clinically silent locally advanced pheochromocytoma following a computed tomography-guided biopsy of a left retroperitoneal mass discovered during evaluation for persistent lower back pain. Biochemical evaluation revealed normal 24-hour urinary metanephrines despite markedly elevated chromogranin A levels. Imaging demonstrated an 80 × 76 mm left adrenal mass with locoregional invasion. Histopathological and immunohistochemical analyses confirmed pheochromocytoma.
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Registered trials
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