ReviewInternational journal of molecular medicine2026
Role of aging‑related cytokines in neurodegenerative disease (Review).
Review in International journal of molecular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neurodegenerative diseases (NDs) are neurological disorders marked by neuronal damage and functional decline, notably affecting human quality of life and imposing substantial burdens on healthcare systems. The increasing prevalence of NDs is associated with intensification of population aging worldwide. Consequently, there is need to investigate effective prevention and treatment strategies. Aging is a risk factor for NDs. Throughout the aging process, alterations in the expression of specific cytokines occur, such as IL‑6 and tumor necrosis factor‑α, precipitating a cascade of chronic inflammatory responses. The present study provides a comprehensive review of the alterations in cytokines associated with aging in NDs and the chronic inflammatory responses they elicit. Furthermore, it explores the mechanisms by which these cytokines contribute to neuroinflammation, neuronal damage and cell death, thereby proposing a novel research direction for the treatment of NDs through cytokine regulation.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.