Evidence mapPaperPMID 41930573Full record

ReviewOncology reports2026

T cell fate regulation in EBV‑associated nasopharyngeal carcinoma (Review).

Liuyang Zhang, Shun Ding, Dongzhui Chen, Benchi Cai, Zhonglin Mu

Abstract readReview
In one paragraph

Review in Oncology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Liuyang Zhang *Department of Otolaryngology, Head and Neck Surgery, The First Affiliated Hospital, Hainan Medical University, Haikou, Hainan 570102, P.R. China.
Shun Ding *Department of Otolaryngology, Head and Neck Surgery, The First Affiliated Hospital, Hainan Medical University, Haikou, Hainan 570102, P.R. China.
Dongzhui Chen *Department of Pediatrics, First Affiliated Hospital of Hainan Medical University, Haikou, Hainan 570102, P.R. China.
Benchi CaiDepartment of Neurology, Hainan General Hospital, Hainan Medical University, Haikou, Hainan 570311, P.R. China.
Zhonglin MuDepartment of Otolaryngology, Head and Neck Surgery, The First Affiliated Hospital, Hainan Medical University, Haikou, Hainan 570102, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nasopharyngeal carcinoma, a malignancy associated with Epstein‑Barr virus, presents a complex immune editing landscape in which T cell fate determination carries out a central role. T cell metabolic exhaustion, Epstein‑Barr virus antigen presentation and tertiary lymphoid structure remodeling are important in the context of tumor immune evasion. Although individual mechanisms have been extensively studied, their interplay and collective contribution to immune editing remain incompletely understood. The present review summarizes the current advances in nasopharyngeal carcinoma immune editing, with a focus on the molecular network underlying T cell fate decisions. How these mechanisms can be leveraged to develop novel immunotherapeutic strategies is further discussed. By integrating recent findings, the present review aims to offer new insights into the intricate immune landscape of nasopharyngeal carcinoma and to provide a theoretical basis for improving immunotherapy efficacy.

Indexed as

Epstein-Barr Virus InfectionsHerpesvirus 4, HumanNasopharyngeal CarcinomaNasopharyngeal NeoplasmsT-LymphocytesAntigen PresentationHumansImmunotherapyT-Cell ExhaustionTumor Escapeantigen presentationEpstein‑Barr virusimmune editingmetabolic reprogrammingnasopharyngeal carcinomaT cell exhaustiontertiary lymphoid structures

Identifiers

PMID41930573
PMCPMC13087864

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.