ReviewCurrent opinion in neurobiology2026
The hormonal and neural control of maternal aggression.
Review in Current opinion in neurobiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Neural circuits for mammalian parental behaviour.Nature reviews. Neuroscience · 2026Review
- Rodent models of aggression: from mechanisms to clinical translation.Der Nervenarzt · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
In mice and many other species, aggression levels are low in virgin females but increase dramatically during lactation to protect vulnerable offspring. This aggression, aimed at protecting the young, is known as maternal aggression. It emerges abruptly after parturition, peaks during early lactation, and declines after weaning. Given its stereotyped temporal profile, hormones associated with pregnancy and lactation are believed to play critical roles in its rise and fall. In addition, maternal aggression diminishes within hours of pup separation and rapidly recovers upon pup reunion, indicating a secondary, pup-dependent regulation of its expression. Here, we review current knowledge of the female aggression circuit and the hormonal and neural mechanisms that reshape it during pregnancy and lactation. We propose a two-step model in which pregnancy-associated sex hormone surges refine the aggression circuit, while lactation-associated neuropeptide signals gate circuit output in response to the need to protect offspring.
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Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.