Evidence mapPaperPMID 41933019Full record

ArticleNPJ digital medicine2026

Sensor-based digital health technologies to capture endpoints in recent clinical trials: a scoping review.

Julia Garcia, Margaret M Mordin, Bidur Banjara, Cassondra Saande, Katelyn R Keyloun, Jessica L Abel, Ari Gnanasakthy, Bill Byrom

Abstract read
In one paragraph

Article in NPJ digital medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Julia GarciaHealth Economics and Outcomes Research Strategy, AbbVie, Irvine, CA, USA. Julia.k.garcia@abbvie.com.
Margaret M MordinRTI Health Solutions, Durham, NC, USA.
Bidur BanjaraRTI Health Solutions, Durham, NC, USA.
Cassondra SaandeRTI Health Solutions, Durham, NC, USA.
Katelyn R KeylounDigital and Data Strategy, AbbVie, Irvine, CA, USA.
Jessica L AbelPatient Centered Outcomes Research, AbbVie, Florham Park, NJ, USA.
Ari GnanasakthyRTI Health Solutions, Durham, NC, USA.
Bill ByromeCOA Science, Signant Health, Nottingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sensor-based digital health technologies (DHTs) enable continuous collection of physiological data, sensor-based functional outcomes, and performance outcomes in clinical and real-world settings. However, cross-therapeutic reviews examining sensor-based DHTs as outcome measurement tools rather than interventions in recent pharmaceutical and device trials are lacking, limiting understanding of practical implementation and utility in COA development for use in clinical trials. To address this gap, a scoping review was conducted that encompassed clinical studies that used sensor-based DHTs and were published in MEDLINE, MEDLINE In-Process, and PsycINFO databases from January 2021-December 2023. In total, 48 studies were included, and most (n = 38; 79%) collected sensor-based physiological data, with continuous glucose monitoring (CGM) being the most frequent. Additionally, 12 studies (25%) described sensor-based outcomes, such as physical activity and sleep; 2 studies collected both sensor-based physiological data and clinical outcomes. Our findings highlight the use of sensor-based DHTs in clinical research to measure patient outcomes and describe challenges in implementing these technologies in clinical trials.

Identifiers

PMID41933019
PMCPMC13230522

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.