Evidence map›Paper›PMID 41933334›Full record

ArticleMalaria journal2026

Fatal and non-fatal health outcomes of malaria among reproductive age women in Eastern Sub-Saharan Africa, from 1990 to 2023.

Sebsibe Tadesse, Wolyu Korma, Abdulbasit Sherfa, Jemal Bedewi, Embay Amare Alemseged, Yonas Angaw, Lechisa Assefa, Yohannes Fekadu, Girma Ashenafi, Debela Tsegaye and 1 more

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Article in Malaria journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Sebsibe TadesseSchool of Public Health, Institute of Health, Bule Hora University, Bule Hora, Ethiopia.
Wolyu KormaDepartment of Public Health, College of Medicine and Health Sciences, Werabe University, Werabe, Ethiopia. wolyukorma1444@gmail.com.
Abdulbasit SherfaDepartment of Public Health, College of Medicine and Health Sciences, Werabe University, Werabe, Ethiopia.
Jemal BedewiDepartment of Public Health, College of Medicine and Health Sciences, Wolkite University, Wolkite, Ethiopia.
Embay Amare AlemsegedDepartment of Public Health, College of Medicine and Health Sciences, Adigrat University, Adigrat, Ethiopia.
Yonas AngawSchool of Public Health, College of Medicine and Health Sciences, Adigrat University, Adigrat, Ethiopia.
Lechisa AssefaDepartment of Environmental Health, Institute of Health, Bule Hora University, Bule Hora, Ethiopia.
Yohannes FekaduDepartment of Epidemiology, School of Public Health, Institute of Health, Bule Hora University, Bule Hora, Ethiopia.
Girma AshenafiDepartment of Medical Laboratory Science, Institute of Health, Bule Hora University, Bule Hora, Ethiopia.
Debela TsegayeDepartment of Health Informatics, School of Public Health, Institute of Health, Bule Hora University, Bule Hora, Ethiopia.
Tibeso GemechuDepartment of Medical Laboratory Science, Institute of Health, Bule Hora University, Bule Hora, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalaria is a life-threatening disease that is transmitted by the bites of infected female Anopheles mosquitoes. Women of reproductive age (WRA) are a more vulnerable group to malaria, which increases the risk of severe anemia, maternal death, and unfavorable birth outcomes. However, only limited comprehensive studies are available in the Eastern Sub-Saharan African (ESSA) region. The Global Burden of Diseases (GBD) 2023 estimates were to assess the fatal and non-fatal health outcomes of malaria among WRA in ESSA region from 1990 to 2023.

methodThe Cause of Death Ensemble Model (CODEm) modeling platform was used to estimate mortality and Years of Life Lost (YLLs) in the GBD 2023 study. Years Lived with Disability (YLDs), prevalence, and incidence of malaria disease was estimated by using Bayesian meta-regression for Disease modeling. The net change from 1990 to 2023 was evaluated by percentage change. All estimates were presented together with the 95% uncertainty intervals (95% UIs).

resultsIn 2023, the highest prevalence rate of malaria among WRA was recorded in Mozambique [19627 cases per 100,000 WRA (95% UI: 12,347, 27,601)]. However, the lowest prevalence rate was estimated in Eritrea [842 (95% UI: 450, 1430)] and Rwanda [1603 (95% UI: 587, 3180)]. Mozambique had the highest incidence rate [16076 new cases per 100,000 WRA (95% UI: 11,890, 21,714)], whereas Eritrea had the lowest rate [2267 new cases per 100,000 WRA (95% UI: 962, 4539)]. The highest rates of mortality, YLLs and Disability-Adjusted Life Years (DALYs) were estimated in Mozambique, whereas the lowest rates were recorded in Ethiopia. There were substantial reductions in the rates throughout the region in 2023 compared to 1990, except in Djibouti and Ethiopia.

conclusionThis study has revealed that there was substantial reduction in the rates of non-fatal and fatal health outcomes of malaria among WRA in the ESSA region in 2023 compared to 1990. However, the rates remain high and heterogeneous across the region. Therefore, strengthening the health service system and sustaining strong malaria control programs across the countries are crucial to end malaria epidemics by 2030.

Indexed as

MalariaAdolescentAdultAfrica South of the SaharaFemaleHumansIncidenceMiddle AgedPrevalenceYoung AdultEastern Sub-Saharan AfricaMalariaWomen of reproductive age

Identifiers

PMID41933334
PMCPMC13173719

What Socratic holds

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.