High and low residual feed intake: Associations with meat quality, energy-lipid metabolism, and immune performance in late-laying hens.

Zhouyang Gao, Yuhui Qin, Jing Yang, Yuchen Jie, Jiangxia Zheng, Guiyun Xu

Abstract read

In one paragraph

Article in Poultry science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Zhouyang GaoCollege of Animal Science and Technology, China Agricultural University, Beijing 100193, China.

Yuhui QinCollege of Animal Science and Technology, China Agricultural University, Beijing 100193, China.

Jing YangCollege of Animal Science and Technology, China Agricultural University, Beijing 100193, China.

Yuchen JieCollege of Animal Science and Technology, China Agricultural University, Beijing 100193, China.

Jiangxia ZhengCollege of Animal Science and Technology, China Agricultural University, Beijing 100193, China.

Guiyun XuCollege of Animal Science and Technology, China Agricultural University, Beijing 100193, China. Electronic address: ncppt@cau.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Residual feed intake (RFI) is considered a more accurate indicator of feed efficiency and is widely applied to determine the production performance of poultry. However, limited research has been conducted on the effects of RFI on the meat quality of hens. This study explored how different RFIs regulate meat quality in late-laying hens, dividing them into lowest (LRFI) and highest (HRFI) RFI groups. Regarding production performance, two groups showed no significant differences in body weight and egg production; however, the LRFI group exhibited reduced accumulation of liver and abdominal fat and more tender with a high intramuscular fat content. Mechanistic analysis demonstrated that the elevated levels of short-chain fatty acids (SCFAs) in the LRFI group activated FFAR2/3 signaling, which subsequently triggered the NRF1/AMPK/mTOR axis. Activation of this axis accelerated central carbon metabolism and enhanced mitochondrial oxidative metabolism as well as fatty acid β-oxidation. This coordinated metabolic reprogramming improved antioxidant capacity and maintained immune homeostasis, ultimately promoting a more favorable lipid deposition pattern and enhancing meat quality.

Indexed as

ChickensEatingEnergy MetabolismLipid MetabolismMeatAnimal FeedAnimalsDietFemaleImmune performanceLaying henLipid and energy metabolismMeat qualityResidual feed intake

Identifiers

PMID41933535

DOI10.1016/j.psj.2026.106861

PMCPMC13068826

What Socratic holds

Textmetadata

LicenceCC BY-NC-ND

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.