Evidence map›Paper›PMID 41935035›Full record

Articlenpj aging2026

Elevated trimethylamine levels characterize impaired muscle mass response to leucine-enriched protein supplementation in older adults at risk of sarcopenia.

Hsiang-Yu Tang, Chi-Jen Lo, Hung-Yao Ho, Cheng-Hung Yang, Chen-Yu Chang, Yu-Hsuan Ho, Ji-Tseng Fang, Chih-Ming Lin, Mei-Ling Cheng

Abstract read
In one paragraph

Article in npj aging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hsiang-Yu TangMetabolomics Core Laboratory, Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan.
Chi-Jen LoMetabolomics Core Laboratory, Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan.
Hung-Yao HoMetabolomics Core Laboratory, Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan.
Cheng-Hung YangMetabolomics Core Laboratory, Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan.
Chen-Yu ChangGraduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Yu-Hsuan HoDepartment of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Ji-Tseng FangDivision of Critical Care Nephrology, Kidney Institute, Chang Gung Memorial Hospital, Linkou Medical Center, Chang Gung University, Taoyuan, Taiwan.
Chih-Ming LinCollege of Medicine, Chang Gung University, Taoyuan, Taiwan.
Mei-Ling ChengMetabolomics Core Laboratory, Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan. chengm@mail.cgu.edu.tw.

Funding

Chang Gung Memorial Hospital XMRPG3L102Chang Gung Memorial Hospital, Linkou CMRPD1P0171Chang Gung University URRPD1P0141Ministry of Education in Taiwan EMRPD1N0581National Science and Technology Council 110-2320-B-182-007National Science and Technology Council 113-2320-B-182-018-MY3
6 · The paper itself

Abstract

Leucine-enriched supplementation is a primary intervention for sarcopenia, yet individual responses vary. We integrated

Identifiers

PMID41935035
PMCPMC13230888

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.