Evidence map›Paper›PMID 41936641›Full record

ReviewProtoplasma2026

Nanoencapsulated EO-based drug delivery for pest control: from chemistry to formulation design.

Wajid Zaman, Asma Ayaz, Muhammad Zafar, Adnan Amin

Abstract readReview
PubMed Publisher
In one paragraph

Review in Protoplasma, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wajid ZamanDepartment of Life Sciences, Yeungnam University, Gyeongsan, 38541, Republic of Korea.
Asma AyazFaculty of Sports Science, Ningbo University, Ningbo, 315211, China.
Muhammad ZafarDepartment of Plant Sciences, Quaid-i-Azam University, Islamabad, 45320, Pakistan.
Adnan AminDepartment of Life Sciences, Yeungnam University, Gyeongsan, 38541, Republic of Korea. adnan.amin@yu.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rising resistance, regulatory pressure, and ecological costs of synthetic pesticides have accelerated interest in essential oil (EO) based biopesticides. Yet translation is constrained by EO volatility, low water miscibility, photo-oxidation, and rapid dissipation. This review consolidates advances in EO chemistry and nanoformulation to articulate newer drug design thereby linking molecular composition to delivery performance and agronomics. We summarize representative bioactives (e.g., thymol, carvacrol, eugenol, cinnamaldehyde, citral, menthol, and 1,8-cineole) and emphasize mechanistic pathways underlying insecticidal and antimicrobial action, including membrane perturbation, neuromodulation (acetylcholinesterase and octopaminergic signaling), respiratory/metabolic disruption, and repellency etc. We then compared various nanoencapsulation platforms, nanoemulsions, biopolymer and polymeric nanocapsules, lipid carriers (solid lipid nanoparticles and nanostructured lipid carriers), cyclodextrin complexes, and emerging metal–organic framework (MOF) systems as a common framework. By mapping formulation choices, performance trade-offs and reporting gaps are identified that hinder cross-study comparability. Further, commercial EO product blends including thyme–oregano, clove–cinnamon, citral-rich lemongrass formulations are discussed along with practical barriers to adoption, including shelf-life qualification, scalable manufacturing. Particular attention is given to environmental fate, residue dynamics, and compatibility with integrated pest management. Finally, we outline research priorities for standardized characterization, realistic exposure testing and field-validated efficacy to accelerate EO-based nanopesticides in sustainable pest management.

Indexed as

Drug Delivery SystemsNanocapsulesOils, VolatilePest ControlAnimalsDrug CompoundingNanocapsulesOils, VolatileMetal-Organic FrameworksNanopesticidePest control; terpenoidsScale up

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.