Evidence map›Paper›PMID 41937539›Full record

ReviewInvestigative radiology2026

It Is All About Energy-the Changing Role of X-ray Photons in Photon-counting Detector Computed Tomography: What the Radiologist Needs to Know About kV and keV.

Eva J I Hoeijmakers, Bibi Martens, Joachim E Wildberger, Thomas G Flohr, Cécile R L P N Jeukens

Abstract readReview
In one paragraph

Review in Investigative radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eva J I HoeijmakersORCID 0009-0007-7026-3112
Bibi Martens
Joachim E Wildberger
Thomas G Flohr
Cécile R L P N Jeukens

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CT image quality is strongly influenced by the energy of the x-ray beam. The tube voltage (kV) determines a polyenergetic x-ray spectrum, which affects both image contrast and noise in conventional energy-integrating detector CT (EID-CT) imaging. In photon-counting detector CT (PCD-CT), spectral data sets are always available by default, and virtual monoenergetic images (VMI) can be reconstructed at any specific photon energy (keV). This enables radiologists to tailor energy selection to dedicated clinical tasks, achieving an optimal balance between contrast, noise, and radiation dose, and ultimately enhancing diagnostic confidence. This article educates the reader on the differences between polyenergetic and monoenergetic images to provide radiologists with practical insights into optimizing spectral imaging protocols and leveraging keV differences in routine clinical practice. Using an anthropomorphic phantom with iodine rods, differences in image quality, specifically image contrast and noise, are demonstrated between polyenergetic EID-CT and PCD-CT VMIs.

Indexed as

PhotonsRadiographic Image Interpretation, Computer-AssistedTomography, X-Ray ComputedHumansPhantoms, ImagingRadiation DosageSensitivity and SpecificityX-Rayscomputed tomographyimage qualitykVmonoenergetic CTphoton-counting CT

Identifiers

PMID41937539
PMCPMC13629652

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.