Evidence map›Paper›PMID 41938030›Full record

ArticleOrthopedic reviews2026

Platelet-Rich Plasma in the Treatment of Knee Osteoarthritis: A Bibliometric Analysis of Global Research Trends.

Haichen Zhou, Latha Ganti

Abstract read
In one paragraph

Article in Orthopedic reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Haichen ZhouWarren Alpert Medical School of Brown University.
Latha GantiWarren Alpert Medical School of Brown University.ORCID https://orcid.org/0000-0001-7717-3864

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Knee osteoarthritis (OA) represents a major cause of pain and disability among older adults. Platelet-rich plasma (PRP) has emerged as a promising biologic therapy aimed at modulating inflammation and promoting cartilage repair. As the clinical use of PRP has expanded, a rapidly growing body of literature has developed examining its efficacy and mechanisms of action in knee OA. Bibliometric analysis provides a useful method to evaluate research productivity, collaborative networks, and emerging trends within a scientific field. Methods: A bibliometric analysis was conducted using the Web of Science Core Collection database to identify publications related to PRP and knee osteoarthritis. The search strategy included the terms ("platelet-rich plasma" OR "PRP") AND ("knee osteoarthritis" OR "knee OA"). No time restrictions were applied. Data regarding authorship, institutions, countries, journals, and funding sources were extracted. Network visualization of co-authorship relationships was performed using VOSviewer (version 1.6.20). Descriptive analyses and graphical summaries were generated using Microsoft Excel. Results: A total of 2,116 publications were identified. The co-authorship network demonstrated several highly influential investigators, including Filardo, Kon, Cole, and Boffa. Arthroscopy: The Journal of Arthroscopic and Related Surgery and the American Journal of Sports Medicine were the most prolific journals, accounting for 95 and 93 publications respectively. The United States produced the highest number of publications (602), followed by China, Italy, and Spain. Institutional analysis demonstrated strong contributions from Harvard University and Rush University. Funding support was most frequently provided by the National Natural Science Foundation of China and the U.S. National Institutes of Health. Conclusion: Research on PRP for knee osteoarthritis has expanded substantially over the past decade, with contributions concentrated in a small number of countries and academic institutions. Continued collaboration, methodological standardization, and high-quality clinical trials will be essential to clarify the therapeutic role of PRP in the management of knee osteoarthritis.

Indexed as

bibliometric analysisknee osteoarthritisplatelet-rich plasma

Identifiers

PMID41938030
PMCPMC13048843

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.