Evidence map›Paper›PMID 41939199›Full record

ArticleFrontiers in nutrition2026

The association between early-life nutrition and palatine tonsil grading in preschool children: a cross-sectional study.

Guangwei Guo, Wanyun Yan, Ruifa Zhou, Lianhua Lü, Yitong Lu, Yuyong Pan, Jianhui Luo, Chengquan Wu, Meilian Chen, Dongmin Xie and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Guangwei Guo *Department of Otorhinolaryngology, Yulin Maternal and Child Health Care Hospital, Yulin, Guangxi, China.
Wanyun Yan *Department of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Ruifa ZhouDepartment of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Lianhua LüDepartment of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Yitong LuDepartment of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Yuyong PanDepartment of Otorhinolaryngology, Yulin Maternal and Child Health Care Hospital, Yulin, Guangxi, China.
Jianhui LuoDepartment of Otorhinolaryngology, Yulin Maternal and Child Health Care Hospital, Yulin, Guangxi, China.
Chengquan WuDepartment of Otorhinolaryngology, Yulin Maternal and Child Health Care Hospital, Yulin, Guangxi, China.
Meilian ChenDepartment of Otorhinolaryngology, Yulin Maternal and Child Health Care Hospital, Yulin, Guangxi, China.
Dongmin XieDepartment of Otorhinolaryngology, Yulin Maternal and Child Health Care Hospital, Yulin, Guangxi, China.
Jiping SuDepartment of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Early-life nutritional factors play a crucial role in child health, but their association with palatine tonsil grading is not well understood. This study aimed to investigate the relationship between early-life nutrition and palatine tonsil grading in preschool children. Methods: A cross-sectional study of 2,786 children from 17 kindergartens in Yulin City was conducted. Palatine tonsil grading was assessed via physical examination, and early-life nutritional data were collected through parent questionnaires, with 816 valid matches to examination records. Associations between early-life nutrition and palatine tonsil grading were analyzed using age-adjusted ordered logistic regression, stratified by sex. Results: Among 2,786 preschool children aged 2-7 years, palatine tonsillar hypertrophy (grades III-IV) was observed in 5.28%. Females aged 2-4 years had a significantly lower risk than males (OR = 0.438, Conclusion: Our results suggested a possible association between exclusive formula feeding during 0-6 months and a higher palatine tonsil grading in females, while larger studies are needed for confirmation. Other early nutritional exposures showed no significant effect, and no associations were observed in males.

Indexed as

breastfeedingcomplementary food introductionearly-life nutritionformula feedingpalatine tonsil grading

Identifiers

PMID41939199
PMCPMC13043436

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.