ReviewInternational journal of endocrinology2026
Endocrine-Taste Crosstalk: A Scoping Review on Thyroid Dysfunction and Its Genetic Links to Taste Receptors With Dysgeusia.
Review in International journal of endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Endocrine-Taste Crosstalk: A Scoping Review on Thyroid Dysfunction and Its Genetic Links to Taste Receptors With Dysgeusia.International journal of endocrinology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thyroid disorders are a common endocrine condition globally, affecting various bodily systems and metabolism. Changes in thyroid function affect smell and taste; yet, many patients remain unaware of their dysosmia and dysgeusia. Currently, there is a lack of detailed information regarding changes in physiological taste thresholds across different taste modalities or the genetic polymorphism(s) associated with them. This review underscores the association between genetic polymorphism in taste receptor genes with altered taste sensation in thyroid disease. Data bases from 1990 to 2025 were searched with appropriate Medical Subject Headings (MeSH) terms and Boolean operators (PubMed-MEDLINE, Google Scholar, Scopus, Web of Science, and Embase). A total of 446 titles were retrieved. After elimination and thorough review, 18 articles were included, of which 3 articles met the inclusion and exclusion criteria. Understanding genetic changes in individuals with thyroid dysfunction can raise clinician awareness in identification and take proactive measures to educate, screen, and chart treatment protocols. Studies on agonist considered to be the novel drug targets can act on these taste receptors or those resistant to conventional drugs in the treatment of thyroid dysfunction opens new avenues for understanding thyroid regulation and potential drug development targeting Taste 2 Receptors (TAS2Rs).
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.