ReviewCureus2026
Near-Infrared Fluorescence Guidance With Indocyanine Green in Adrenal-Sparing Surgery: A Systematic Review.
Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cortical-sparing adrenal surgery might require additional intraoperative navigation to optimize outcomes. Near-infrared fluorescence imaging with indocyanine green (NIR/ICG) has emerged as a promising adjunct to support this goal. A systematic search of international and Russian databases identified clinical and experimental studies (2013-2024) evaluating NIR/ICG during adrenal surgery. Fifteen studies met the inclusion criteria. Due to data heterogeneity and limited comparative evidence, a systematic review without meta-analysis was performed. Since the first report in 2013, subsequent studies consistently demonstrated differential fluorescence between adrenal tumors and normal tissue. NIR/ICG improved visualization of adrenal anatomy, aided margin delineation, facilitated tissue dissection, and enabled assessment of perfusion in residual adrenal tissue during cortical-sparing procedures. NIR/ICG is a safe and promising tool for intraoperative navigation in adrenal surgery. However, further research is needed to clarify fluorescence interpretation, define correlations with tumor biology, standardize protocols, and validate its role in assessing adrenal parenchyma viability.
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