Evidence map›Paper›PMID 41939890›Full record

ArticleFrontiers in immunology2026

GPX2+ tumor cells recruit LGALS1+ B cells via CCL26-CCR3 axis to promote immunosuppression and tumor progression in hepatocellular carcinoma.

Liang Lin, Shiye Yang, Jixiang Zhang, Guodu Chen, Wuhan Zhou, Dongxing Chen, Jiafei Chen

Abstract read
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Liang Lin *Department of Hepatobiliary Surgery, The First Hospital of Putian City, Putian, Fujian, China.
Shiye Yang *Department of Comprehensive Surgery, Nantong First People's Hospital, Affiliated Hospital 2 of Nantong University, Nantong, Jiangsu, China.
Jixiang Zhang *General Surgery Department I, Zhongshan City People's Hospital, No. 2, Zhongshan, Guangdong, China.
Guodu ChenDepartment of Hepatobiliary Surgery, The First Hospital of Putian City, Putian, Fujian, China.
Wuhan ZhouDepartment of Hepatobiliary Surgery, The First Hospital of Putian City, Putian, Fujian, China.
Dongxing ChenDepartment of Hepatobiliary Surgery, The First Hospital of Putian City, Putian, Fujian, China.
Jiafei ChenDepartment of Hepatobiliary Surgery, The First Hospital of Putian City, Putian, Fujian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The molecular link between Hepatitis B virus (HBV) infection and hepatocellular carcinoma (HCC) progression remains elusive. Here, we identify glutathione peroxidase 2 (GPX2) as a pivotal mediator of this process. Single-cell analysis of HBV-positive HCC reveals a distinct GPX2

Indexed as

B-LymphocytesCarcinoma, HepatocellularChemokines, CCGlutathione PeroxidaseLiver NeoplasmsAnimalsCell Line, TumorDisease ProgressionHepatitis B virusHumansMiceNeoplastic Stem CellsOxidative StressReactive Oxygen SpeciesSignal TransductionChemokines, CCGlutathione PeroxidaseGPX2 protein, humanReactive Oxygen SpeciesB cellCSCsGPX2HBV-positive HCCROS

Identifiers

PMID41939890
PMCPMC13047122

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.