Evidence map›Paper›PMID 41939907›Full record

ArticleFrontiers in immunology2026

Enrichment of

S Jayaraman, S S Mahalingam, Z Zhu, F Faddoul, A Paes da Silva, R Asaad, N Bhaskaran, E Schneider, T Taylor, S Horne and 4 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

S JayaramanDepartment of Biological Sciences, School of Dental Medicine, Case Western Reserve University, Cleveland, OH, United States.
S S MahalingamDepartment of Biological Sciences, School of Dental Medicine, Case Western Reserve University, Cleveland, OH, United States.
Z ZhuDepartment of Population & Quantitative Health Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.
F FaddoulAdvanced Education in General Dentistry, School of Dental Medicine, Case Western Reserve University, Cleveland, OH, United States.
A Paes da SilvaDepartment of Periodontics, School of Dental Medicine, Case Western Reserve University, Cleveland, OH, United States.
R AsaadUniversity Hospitals Cleveland Medical Center AIDS Clinical Trials Unit, Cleveland, OH, United States.
N BhaskaranDepartment of Biological Sciences, School of Dental Medicine, Case Western Reserve University, Cleveland, OH, United States.
E SchneiderDepartment of Biological Sciences, School of Dental Medicine, Case Western Reserve University, Cleveland, OH, United States.
T TaylorCenter for Global Health and Diseases, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.
S HorneCenter for Global Health and Diseases, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.
A YooCenter for Global Health and Diseases, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.
L ZhangDepartment of Population & Quantitative Health Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.
A BurgenerCenter for Global Health and Diseases, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.
Pushpa PandiyanDepartment of Biological Sciences, School of Dental Medicine, Case Western Reserve University, Cleveland, OH, United States.

Funding

METABOLOME ANALYSES OF SALIVA SAMPLES FROM HIV+ PATIENTS ON cARTR01DE026923 · NIDCR · CASE WESTERN RESERVE UNIVERSITY · PI Pushpa Pandiyan · 2017 to 2026
$4.5M
NIDCR NIH HHS R01 DE026923
6 · The paper itself

Abstract

Age-associated T cell dysfunction is a defining feature of inflammaging and immunosenescence, the progressive decline in immune competence observed with advancing age. Here we identified the association between aging (defined as age >60) and fungal dysbiosis, notably characterized by increased colonization of

Indexed as

AgingCandidaDysbiosisMouth MucosaT-Lymphocytes, RegulatoryAdultAgedFemaleForkhead Transcription FactorsHumansLymphocyte ActivationMaleMiddle AgedForkhead Transcription FactorsFOXP3 protein, humanCandidainflammagingmucosal immunityoral microbiomeTregs (Regulatory T cells)

Identifiers

PMID41939907
PMCPMC13043350

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.