Evidence map›Paper›PMID 41940526›Full record

ArticleActa neuropsychiatrica2026

Early health economic assessment of eLi

Ole Köhler-Forsberg, Thea Kirkegaard Kjær, Andrew A Nierenberg, Tom Bschor, Lars Vedel Kessing, Christian Kraft, Lars Ehlers

Abstract read
In one paragraph

Article in Acta neuropsychiatrica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ole Köhler-ForsbergPsychosis Research Unit, https://ror.org/040r8fr65Aarhus University Hospital, Denmark.ORCID https://orcid.org/0000-0001-5121-1287
Thea Kirkegaard KjærNordic Institute of Health Economics A/S, Denmark.ORCID https://orcid.org/0009-0002-0136-8627
Andrew A NierenbergDauten Family Center for Bipolar Treatment Innovation, Massachusetts General Hospital, Harvard Medical School, USA.
Tom BschorDepartmen of Psychiatry, University Hospital, Technical University of Dresden, Germany.
Lars Vedel KessingPsychiatric Centre Copenhagen, Denmark.
Christian KraftDepartment of Clinical Medicine, https://ror.org/01aj84f44Aarhus University, Denmark.
Lars EhlersNordic Institute of Health Economics A/S, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEarly economic evaluations (EEE) can evaluate the economic potential of new innovative healthcare solutions. We present a methodological framework for EEE in bipolar disorder and use eLi

methodsA decision-analytic model evaluated the costs and consequences of eLi

resultsAssuming 28,000 patients with bipolar disorder whereof 10,000 are treated with lithium, a 2.5% reduction in number of hospitalisations and suicides are sufficient for eLi

conclusionEEE can evaluate the health economic potential of new innovative methods, supporting early investment decisions and guiding research. eLi

Indexed as

Antimanic AgentsBipolar DisorderCost-Benefit AnalysisLithiumLithium CompoundsCost-Effectiveness AnalysisDenmarkHospitalizationHumansQuality-Adjusted Life YearsAntimanic AgentsLithiumLithium Compounds12-h lithium levelbipolar disorderearly health economic assessmentlithiumlithium trough level

Identifiers

PMID41940526
PMCPMC13139936

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.