ReviewAmerican journal of reproductive immunology (New York, N.Y. : 1989)2026
Innate Immune Protection Against HIV in the Female Genital Tract.
Review in American journal of reproductive immunology (New York, N.Y. : 1989), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Special Issue on New Horizons in HIV and Reproductive Health Research.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026Article
- Mucosal Dynamics Contributing to Innate Immune Responses to HIV in the Human Female Genital Tract.Viruses · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
problemImmune responses in the female genital mucosa are regulated to coordinate reproductive function and protection against infections. The female genital tract serves as one of the main portals of entry for sexually transmitted infections, including HIV. Under physiological conditions the rates of HIV transmission per sexual act are relatively low, but susceptibility to infection increases significantly with genital inflammation. Understanding innate immune protection, the mechanisms that trigger genital inflammation, and how innate immunity is altered under inflammatory conditions is needed to develop preventative strategies. METHOD OF STUDY: Based on a literature review of PubMed, this review is focused on recent advances in our understanding of innate immune protection in the human female genital tract with an emphasis on mechanisms involved in antiviral protection and HIV acquisition.
conclusionsWe highlight the roles of epithelial barriers, mucus, innate receptors, and innate immune cell populations in the human female genital mucosa under steady-state conditions and the initial responses upon encountering HIV.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.