ReviewDiscover nano2026
Bibliometric and visualized analysis of metal‒organic frameworks in bone tissue engineering and bone diseases.
Review in Discover nano, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundGiven their tunable structures, high porosity, and multifunctional therapeutic potential, metal-organic frameworks (MOFs) have emerged as versatile biomaterials for bone tissue engineering and bone-related diseases. Despite rapid research growth, a systematic and bone-specific bibliometric understanding of its knowledge structure, thematic evolution, and emerging research frontiers remains limited.
methodsPublications on MOFs related to bone tissue engineering and bone diseases (2015-2025) were retrieved from the Web of Science Core Collection. Bibliometric and visualized analyses using Bibliometrix, VOSviewer, and CiteSpace were performed to evaluate publication trends, global contributions, collaboration networks, journals, references, and keyword dynamics. Keyword frequency, co-occurrence clustering, trend topic analysis, thematic mapping, and citation burst detection were integrated to elucidate structural and temporal evolution.
resultsA total of 350 English-language publications were analyzed, showing a marked increase in annual output after 2022 but a decline in average citation rate. China was the most productive country, led by Sichuan University and Shanghai Jiao Tong University, while Australia and Canada achieved higher average citation impacts. Keyword analyses identified bone regeneration and osteogenesis as enduring cores, whereas temporal trends revealed a shift from early material synthesis and drug delivery to function-oriented, clinically motivated research. Emerging topics such as oxidative stress, photothermal therapy, corrosion resistance, and magnesium alloys highlight ongoing therapeutic integration and implant optimization.
conclusionThis study delineates the evolution of MOF-based bone research from material-centered exploration to clinically driven innovation, offering data-driven insights to guide future research and translational applications.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.