Trial reportCNS & neurological disorders drug targets2026
Effect of Dual-task Exercise on Cognition and Dual-task Cost in the Elderly with Mild Cognitive Impairment: A Randomized Pilot Study.
Trial report in CNS & neurological disorders drug targets, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionDual-task (DT) training may enhance cognitive function in older adults with mild cognitive impairment (MCI). Whether virtual reality (VR)-based DT exercise offers advantages over traditional strength-based DT training remains unclear. This study compared their effects on cognition and dual-task cost (DTC) in Older adults from Montes Claros, Brazil.
methodsTwenty independent seniors were randomized to VR-based DT training with Nintendo Wii (n=11) or traditional DT strength exercises (n=9), twice weekly for 26 sessions. Outcomes included global cognition (MoCA), memory (Digit Span), verbal fluency, and DTC (Timed Up and Go + verbal fluency).
resultsPost-intervention analysis revealed distinct effects between training modalities. Participants in the DT group demonstrated significant improvements in working memory (p=0.02), particularly among individuals without MCI, who improved by an average of 1.66 points on the Digit Span backward test. In contrast, those in the VR group experienced a decrease in working memory performance. However, the VR group showed a significant reduction in DTC, with a 9.92% improvement in task execution time (p=0.01), irrespective of MCI status. Meanwhile, the DT exercise group exhibited a 7.06% increase in DTC, suggesting a potential trade-off between cognitive and functional gains depending on the type of dual-task intervention. DISCUSSION: Findings suggest a trade-off: traditional DT training may preferentially benefit a specific cognitive function (working memory), while VR-based DT training may improve task efficiency by lowering DTC.
conclusionTraditional DT exercise appears more effective for working memory, particularly in non-MCI elderly, whereas VR-based DT exercise may better support dual-task performance.
Indexed as
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41941238What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.