Evidence mapPaperPMID 41942585Full record

ArticleScientific reports2026

Beyond the root: licorice (Glycyrrhiza glabra L.) fruit extract modulates oxidative stress and apoptotic markers in PC12 cells.

Parvin Jahanbani, Leila Hosseinzadeh, Matin Mahmoudi, Fereshteh Jalilian, Mahdieh Eftekhari, Masoud Modarresi

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Parvin JahanbaniStudents Research Committee, Kermanshah University of Medical Science, Kermanshah, Iran.
Leila HosseinzadehPharmaceutical Sciences Research Center, School of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Matin MahmoudiStudents Research Committee, Kermanshah University of Medical Science, Kermanshah, Iran.
Fereshteh JalilianPharmaceutical Sciences Research Center, School of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Mahdieh EftekhariPharmaceutical Sciences Research Center, School of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran. mahdieh.eftekhari@gmail.com.
Masoud ModarresiPharmaceutical Sciences Research Center, School of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Funding

Kermanshah University of Medical Sciences 4020639
6 · The paper itself

Abstract

The rising global prevalence of neurodegenerative disorders underscores the urgent need for novel therapeutic strategies. Oxidative stress is a well-established central driver in the pathogenesis of conditions like Alzheimer's and Parkinson's disease. While the root of Glycyrrhiza glabra L. (licorice) is a renowned source of natural antioxidants, its fruit remains a largely unexplored reservoir of bioactive compounds with potential neuroprotective properties. This in vitro study aimed to systematically evaluate the neuroprotective potential of different licorice fruit extracts and elucidate the underlying mechanisms against hydrogen peroxide (H

Indexed as

ApoptosisFruitGlycyrrhizaNeuroprotective AgentsOxidative StressPlant ExtractsAnimalsAntioxidantsCell SurvivalFlavonoidsHydrogen PeroxideMembrane Potential, MitochondrialPC12 CellsPlant RootsRatsAntioxidantsFlavonoidsHydrogen PeroxideNeuroprotective AgentsPlant ExtractsAntioxidantGlycyrrhiza glabraLicorice fruitMitochondrial membrane potentialNeuroprotectionOxidative stressPC12 cell

Identifiers

PMID41942585
PMCPMC13216306

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.