Evidence map›Paper›PMID 41942651›Full record

ArticleScientific reports2026

Prognostic value of point-of-care testing for cardiac myosin-binding protein C in early risk assessment of acute myocardial infarction: a prospective cohort study.

Zengguang Chen, Jing Huang, Jing Wang, Yiyang Zhan, Qianwei Sun

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zengguang Chen *Department of Cardiology, The Third Affiliated Hospital of Nanjing Medical University, The Second People's Hospital of Changzhou, Changzhou, Jiangsu, China.
Jing Huang *Graduate Department, Nanjing Medical University, Nanjing, Jiangsu, China.
Jing WangHealth Management Teaching Department, Changzhou Hygiene Vocational Technology College, Changzhou, Jiangsu, China.
Yiyang ZhanDepartment of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu, China. yiyangzhan@sina.com.
Qianwei SunDepartment of Anesthesiology, The Affiliated Hospital of Xuzhou Medical University, Quanshan District, 99 Huaihai West Road, Xuzhou, 221000, Jiangsu, China. 15950670080@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prognostic value of myocardial myosin-binding protein C (cMyC) in acute myocardial infarction (AMI) remains insufficiently studied. To evaluate the association between admission cMyC levels and the risk of 30-day major adverse cardiovascular events (MACE) in patients with AMI. In this prospective, single-center study, patients with AMI admitted between March 2022 and July 2024 were included. cMyC and hs-cTnI were measured by point-of-care testing (POCT) at admission. The primary endpoint was 30-day MACE. Predictive performance was evaluated using ROC analysis and multivariable Cox regression. A total of 285 patients were included, with a 30-day MACE incidence of 27.4%. Admission cMyC was independently associated with 30-day MACE after adjustment for clinical covariates. Exploratory analyses suggested a graded association between cMyC levels and the risk of adverse outcomes. Admission cMyC measured by POCT was independently associated with 30-day MACE in patients with AMI. cMyC may serve as a rapid adjunctive biomarker for early risk stratification, although its incremental predictive value requires further validation.

Indexed as

Carrier ProteinsMyocardial InfarctionPoint-of-Care TestingAgedBiomarkersFemaleHumansMaleMiddle AgedMyosin Binding Protein CPrognosisProspective StudiesRisk AssessmentBiomarkersCarrier ProteinsMyosin Binding Protein CAcute myocardial infarctionMajor adverse cardiovascular eventsMyocardial myosin-binding protein CPoint-of-care testRisk assessment

Identifiers

PMID41942651
PMCPMC13230524

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.