Evidence map›Paper›PMID 41943604›Full record

ArticleEarly intervention in psychiatry2026

Identifying Research Priorities in Early Psychosis: A Collaborative Approach to Shaping the Future of Early Psychosis Clinical Trials in Australia.

Amity E Watson, Stephen J Wood, Ellie Brown, Isabel Zbukvic, Joanna Fitzsimons, Deanna De Cicco, Karine Fernandez, Georgia Williams, Andrew Thompson

Abstract read
In one paragraph

Article in Early intervention in psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Amity E WatsonOrygen, the National Centre of Excellence in Youth Mental Health, Parkville, Victoria, Australia.ORCID https://orcid.org/0000-0002-8336-8622
Stephen J WoodCentre for Youth Mental Health, The University of Melbourne, Parkville, Victoria, Australia.
Ellie BrownOrygen, the National Centre of Excellence in Youth Mental Health, Parkville, Victoria, Australia.ORCID https://orcid.org/0000-0002-1645-5443
Isabel ZbukvicOrygen, the National Centre of Excellence in Youth Mental Health, Parkville, Victoria, Australia.
Joanna FitzsimonsOrygen, the National Centre of Excellence in Youth Mental Health, Parkville, Victoria, Australia.
Deanna De CiccoOrygen, the National Centre of Excellence in Youth Mental Health, Parkville, Victoria, Australia.
Karine FernandezOrygen, the National Centre of Excellence in Youth Mental Health, Parkville, Victoria, Australia.
Georgia WilliamsOrygen, the National Centre of Excellence in Youth Mental Health, Parkville, Victoria, Australia.
Andrew ThompsonOrygen, the National Centre of Excellence in Youth Mental Health, Parkville, Victoria, Australia.

Funding

Wellcome Trust 218254/Z/19/Z
6 · The paper itself

Abstract

introductionPsychotic disorders are major contributors to disability and mortality, disproportionately affecting young people. Despite advances in early psychosis care, there are still barriers to treatment, suboptimal outcomes, and limited therapeutic options. Given limited funding for psychosis research, priority setting that incorporates perspectives from across the sector, but especially those with lived experience, is vital for directing resources. This paper outlines the Australian Early Psychosis Collaborative Consortium's process for identifying priorities to guide early psychosis clinical trial research in Australia.

methodsQualitative data were collected via online surveys and stakeholder workshops with people with lived experience, carers, clinicians and researchers. Content analysis was conducted, followed by iterative refinement and ranking of priority research questions across multiple stages.

resultsSix broad themes and 55 research questions were identified through both the initial survey and stakeholder consultations, culminating in ten research questions for ranking in the final poll. The top-ranked priority was identifying treatments with the most enduring benefits for individuals with early psychosis. Other priorities included: identifying effective treatments for negative symptoms; addressing trauma in psychosis risk and treatment; focusing on supports for neurodevelopmental conditions; understanding and targeting risk factors to prevent psychosis onset; translation of research findings to clinical care; considerations of cultural diversity; and effective support for people leaving early psychosis services.

conclusionThese findings reaffirm the core objective of specialised early intervention for psychosis: to support long-term recovery and improved outcomes. Identified priorities offer direction for future research and resource allocation that reflects diverse stakeholder perspectives.

Indexed as

Behavioral ResearchClinical Trials as TopicEvidence GapsPsychotic DisordersAustraliaHumansQualitative ResearchStakeholder ParticipationSurveys and Questionnairesearly interventionhealth services researchlived experiencepsychotic disordersresearch prioritisationstakeholder participation

Identifiers

PMID41943604
PMCPMC13054207

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.