Evidence map›Paper›PMID 41944809›Full record

ArticleACS chemical biology2026

Cryo-EM Structure of the FtsH Periplasmic Domain Reveals Functional Dynamics.

Günce Göc, Sathish K N Yadav, George Orriss, Ufuk Borucu, Imre Berger, Christiane Schaffitzel, Burak V Kabasakal

Erratum issuedAbstract read
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In one paragraph

Article in ACS chemical biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Günce GöcTurkish Accelerator and Radiation Laboratory, Ankara 06830, Türkiye.ORCID 0000-0002-1963-8317
Sathish K N YadavSchool of Biochemistry, University of Bristol, Bristol BS8 1TD, U.K.
George OrrissSchool of Biochemistry, University of Bristol, Bristol BS8 1TD, U.K.
Ufuk BorucuSchool of Biochemistry, University of Bristol, Bristol BS8 1TD, U.K.
Imre BergerSchool of Biochemistry, University of Bristol, Bristol BS8 1TD, U.K.ORCID 0000-0001-7518-9045
Christiane SchaffitzelSchool of Biochemistry, University of Bristol, Bristol BS8 1TD, U.K.ORCID 0000-0002-1516-9760
Burak V KabasakalTurkish Accelerator and Radiation Laboratory, Ankara 06830, Türkiye.ORCID 0000-0003-3001-9282

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

FtsH, an AAA + metalloprotease that is essential in bacteria and eukaryotic organelles, maintains cellular homeostasis by degrading misfolded and membrane-associated proteins. Here, we report cryo-EM structures of the

Indexed as

ATP-Dependent ProteasesEscherichia coliEscherichia coli ProteinsCryoelectron MicroscopyModels, MolecularPeriplasmProtein ConformationProtein DomainsATP-Dependent ProteasesEscherichia coli ProteinsFtsH protein, E coli

Identifiers

PMID41944809
PMCPMC13097134

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.