Evidence map›Paper›PMID 41944845›Full record

ReviewPediatric radiology2026

Gadolinium-based contrast agents in pediatric MRI: renal safety, risk mitigation, and emerging alternatives.

Matthew M Jones, Amma A Boakye, Nirali Dave, Abbie M Whitman, Monica M Forbes-Amrhein

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Matthew M JonesDepartment of Radiology and Imaging Sciences, Indiana University, 705 Riley Hospital Drive, Room 1053, Indianapolis, IN, 46202, USA. matmjone@iu.edu.
Amma A BoakyeDepartment of Pediatrics, Indiana University, Indianapolis, IN, USA.
Nirali DaveDepartment of Radiology and Imaging Sciences, Indiana University, 705 Riley Hospital Drive, Room 1053, Indianapolis, IN, 46202, USA.
Abbie M WhitmanDepartment of Pediatrics, Indiana University, Indianapolis, IN, USA.
Monica M Forbes-AmrheinDepartment of Radiology and Imaging Sciences, Indiana University, 705 Riley Hospital Drive, Room 1053, Indianapolis, IN, 46202, USA. mforbesa@iu.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gadolinium-based contrast agents (GBCAs) are integral to pediatric magnetic resonance imaging (MRI), yet their use requires thoughtful consideration due to developmental differences in renal function, concerns about gadolinium retention, and the rare but serious risk of nephrogenic systemic sclerosis (NSF). This review summarizes current knowledge on GBCA molecular structure, pediatric-specific pharmacokinetics, and the spectrum of known adverse effects. We discuss practical, evidence-based strategies for risk mitigation, including identifying children at increased risk, avoiding group I and III agents when eGFR is <30 mL/min/1.73 m

Indexed as

ChildContrast mediaGadoliniumInfant, newbornKidneyMagnetic resonance imaging

Identifiers

PMID41944845

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.