Evidence map›Paper›PMID 41944965›Full record

ArticleStress biology2026

Polarisome core component FgPea2 regulates FgBoi2-mediated polarized growth, pathogenicity and environmental stress in Fusarium graminearum.

Xinrui Guo, Pengfang Li, Yunsi Xiao, Jingkun Liang, Cheng Zheng, Chenxuan Huang, Yakubu Saddeeq Abubakar, Zonghua Wang, Huawei Zheng, Jingwan Yan and 1 more

Abstract read
In one paragraph

Article in Stress biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xinrui GuoState Key Laboratory of Agricultural and Forestry Biosecurity, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, Fujian, 350002, China.
Pengfang LiState Key Laboratory of Agricultural and Forestry Biosecurity, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, Fujian, 350002, China.
Yunsi XiaoState Key Laboratory of Agricultural and Forestry Biosecurity, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, Fujian, 350002, China.
Jingkun LiangCollege of Resources and Environment, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.
Cheng ZhengState Key Laboratory of Agricultural and Forestry Biosecurity, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, Fujian, 350002, China.
Chenxuan HuangState Key Laboratory of Agricultural and Forestry Biosecurity, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, Fujian, 350002, China.
Yakubu Saddeeq AbubakarState Key Laboratory of Agricultural and Forestry Biosecurity, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, Fujian, 350002, China.
Zonghua WangState Key Laboratory of Agricultural and Forestry Biosecurity, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, Fujian, 350002, China.
Huawei ZhengMarine and Agricultural Biotechnology Laboratory, College of Geography and Oceanography, Minjiang University, Fuzhou, 350108, China. zhw@mju.edu.cn.ORCID http://orcid.org/0000-0002-8704-2486
Jingwan YanBiotechnology Research Institute, Fujian Academy of Agricultural Sciences, Fuzhou, 350003, China. yjw@fjage.org.
Guo-Dong LuState Key Laboratory of Agricultural and Forestry Biosecurity, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, Fujian, 350002, China. gdlufafu@163.com.

Funding

National Natural Science Foundation of China 31970141National Natural Science Foundation of China 32470209Natural Science Foundation of Fujian Province 2024J02030The project of Minjiang University MJY19019
6 · The paper itself

Abstract

Fusarium graminearum is a devastating plant pathogenic fungus that is the predominant causal agent of Fusarium head blight. Our previous study showed that the polarisome core component FgPea2 regulates polarized growth, deoxynivalenol (DON) production and virulence of F. graminearum. To further investigate the regulatory network of FgPea2, FgPea2-GFP pull down was performed and the anillin-related protein FgBoi2 was identified. FgBoi2 interacts with FgPea2 and exhibits partial co-localization at the hyphal tips of F. graminearum. Interestingly, FgPea2 regulates the polarized localization of FgBoi2-GFP, suggesting that FgPea2 functions upstream of FgBoi2. Furthermore, deletion of FgBOI2 resulted in a significant reduction in vegetative growth, conidiation, DON production and pathogenicity, as well as increased hyphal branching in F. graminearum. Structural analysis revealed that FgBoi2 contains SH3, SAM and PH domains. Further domain deletion experiments showed that the PH domain is crucial for vegetative growth, hyphae branching and polarized localization of FgBoi2. In addition, FgBoi2 negatively regulates the cell wall integrity and oxidative stress response pathways. FgPea2 and FgBoi2 modulate susceptibility to the fungicides tebuconazole, carbendazim, phenamacril and difenoconazole. In conclusion, this study shows that FgPea2 interacts with FgBoi2 and regulates FgBoi2-mediated polarized growth, stress tolerance, pathogenicity and fungicide resistance in F. graminearum.

Indexed as

FgBoi2Fungicide sensitivityFusarium graminearumPathogenicityPolarisomePolarized growth

Identifiers

PMID41944965
PMCPMC13057054

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.