ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2026
Epiretinal membrane prevalence in asymmetrical pseudoexfoliation glaucoma and its impact on glaucoma monitoring parameters including peripapillary vessel density.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo determine the prevalence of epiretinal membrane (ERM) in asymmetrical pseudoexfoliation glaucoma (PXG) and to assess its impact on glaucoma monitoring parameters, including peripapillary radial capillary vessel density (RPC-VD) and macular vessel density (VD). STUDY
designProspective, cross-sectional study.
methodsThe study included 160 eyes from 80 patients with asymmetrical PXG (PX material present in only one eye) and 80 right eyes from age-matched patients with primary open-angle glaucoma (POAG). All participants underwent optical coherence tomography angiography (OCTA) imaging. Differences between PXG, PX-negative fellow eyes, and POAG eyes were analyzed using generalized linear mixed models (GLMMs) to account for inter-eye dependency.
resultsThere were no significant differences between PXG and POAG eyes in terms of age, visual field mean deviation (VF-MD), retinal nerve fiber (RNFL), ganglion cell complex (GCC), RPC-VD or most macular VD parameters (all p > 0.05). However, PXG eyes had a significantly higher risk of ERM than POAG eyes (OR = 5.60, 95% CI: 1.75–17.88, p = 0.004), after adjustment for age, sex, cataract and/or glaucoma surgery, diabetes, hypertension, and prostaglandin use. PX-negative fellow eyes exhibited an intermediate ERM prevalence, higher than in POAG eyes but not significantly different from either PXG or POAG eyes. Among PXG eyes, those with ERM had worse VF-MD (median: -7.62 dB vs. -2.53 dB, p = 0.008) and lower average RPC-VD and macular VD (p < 0.001– 0.008), while RNFL and GCC thicknesses were comparable.
conclusionPXG was associated with a higher prevalence of ERM, and PX-negative fellow eyes may represent an intermediate stage within the pseudoexfoliation spectrum. In PXG eyes, the presence of ERM was associated with worse VF-MD, and reduced RPC-VD and macular VD. Detailed macular imaging and OCTA evaluation may improve the interpretation of VF changes and support clinical follow-up.
Indexed as
Identifiers
41945091What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.