Evidence map›Paper›PMID 41945142›Full record

ArticleSkeletal radiology2026

Regional and depth-dependent associations between subchondral bone and cartilage in hip osteoarthritis: a preliminary [

Jusuk Lee, Koren E Roach, Emma Bahroos, Fei Jiang, Valentina Pedoia, Sharmila Majumdar, Richard B Souza

Abstract read
In one paragraph

Article in Skeletal radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jusuk LeeDepartment of Radiology and Biomedical Imaging, University of California, 185 Berry Street, Suite 350, San Francisco, CA, 94107, USA. jusuk.lee@ucsf.edu.ORCID http://orcid.org/0000-0002-1100-9268
Koren E RoachDepartment of Biomedical Engineering, Schulich School of Engineering, University of Calgary, Calgary, AB, Canada.
Emma BahroosDepartment of Radiology and Biomedical Imaging, University of California, 185 Berry Street, Suite 350, San Francisco, CA, 94107, USA.
Fei JiangDepartment of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.
Valentina PedoiaDepartment of Radiology and Biomedical Imaging, University of California, 185 Berry Street, Suite 350, San Francisco, CA, 94107, USA.
Sharmila MajumdarDepartment of Radiology and Biomedical Imaging, University of California, 185 Berry Street, Suite 350, San Francisco, CA, 94107, USA.
Richard B SouzaDepartment of Radiology and Biomedical Imaging, University of California, 185 Berry Street, Suite 350, San Francisco, CA, 94107, USA.

Funding

Structural, Biochemical and Functional Connectivity in Osteoarthritis using Quantitative Magnetic Resonance Imaging and Skeletal BiomechanicsR01AR069006 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MAJUMDAR, SHARMILA, SOUZA, RICHARD BRIAN · 2016 to 2025
$7.2M
Mentoring Biomechanics Research in OsteoarthritisK24AR072133 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Richard Brian Souza · 2018 to 2026
$1.5M
NIAMS NIH HHS K24 AR072133NIH HHS K24 AR072133NIH HHS R01 AR069006
6 · The paper itself

Abstract

objectiveTo explore regional and depth-dependent associations between subchondral bone metabolic activity and adjacent cartilage composition in individuals with mild-to-moderate hip osteoarthritis using simultaneous [

methodsIn this exploratory cross-sectional study, 14 participants (28 hips) underwent [

resultsHigher T

conclusionsThis preliminary study presents an exploratory framework for assessing region and depth-specific interactions between subchondral bone metabolic activity and cartilage composition in the hip. The observed patterns are hypothesis-generating and warrant confirmation in larger, longitudinal studies.

Indexed as

Cartilage, ArticularMagnetic Resonance ImagingOsteoarthritis, HipPositron-Emission TomographyAgedCross-Sectional StudiesFemaleFluorine RadioisotopesHumansMaleMiddle AgedMultimodal ImagingRadiopharmaceuticalsSodium FluorideFluorine RadioisotopesRadiopharmaceuticalsSodium FluorideBoneCartilageFunctional imagingHipOsteoarthritis

Identifiers

PMID41945142
PMCPMC13267278

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.