ArticleShock (Augusta, Ga.)2026
Cardiovascular Risk Score (SCORE2) Predicts The Incidence and Severity of Cardiac Damage After Polytrauma: How to Identify At-Risk Patients?
Article in Shock (Augusta, Ga.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveCardiac damage predicts poor outcomes in polytrauma (PT). In older patients, cardiovascular risk factors may predispose to post-traumatic cardiac dysfunction. This study examined whether cardiovascular risk correlates with cardiac damage and influences clinical outcomes in PT.
methodsThis study at a German Level 1 Trauma Centre enrolled 59 PT patients upon emergency room admission. Blood samples were taken at the emergency room, 24, 48, 72, 96 hours, and 10 days to assess cardiac damage via troponin T and N-terminal pro-B-type natriuretic peptide. Transthoracic echocardiography (TTE) was performed at 24/48 hours. Cardiovascular risk was evaluated using the Systematic Coronary Risk Evaluation (SCORE)2 algorithm. Subgroup analysis compared cardiac damage in patients with high (SCORE2 >7.5%) versus low risk, and assessed the additional impact of chest trauma.
resultsArrhythmias were observed in 39% of patients, whereas acute repolarization disorder occurred in nearly 19%. TTE revealed wall motion abnormalities in 12%, diastolic dysfunction in 10%, and right ventricular dysfunction in 5%. SCORE2 and lipoprotein(a) significantly correlated with serum levels of troponin T and N-terminal pro-B-type natriuretic peptide. SCORE2 values were associated with nonsurvival, wall motion disorders, diastolic dysfunction, and relaxation disorders ( P < 0.05). A higher incidence of arrhythmias, diastolic dysfunction, and relaxation disorders was observed in the subgroup of high-risk patients with chest trauma. Patients in the high-risk group without chest trauma showed higher nonsurvival rates (50%), which may be strongly influenced by a history of myocardial infarction.
conclusionsCardiovascular risk was significantly associated with cardiac damage markers, TTE abnormalities, and increased mortality. A history of myocardial infarction was associated with higher mortality in PT patients with an elevated SCORE2 risk.
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