Evidence mapPaperPMID 41946972Full record

ArticleJournal of cancer research and clinical oncology2026

Phosphorylated mTOR immunohistochemistry-guided use of temsirolimus in recurrent IDH-wildtype glioblastoma: a real-world retrospective series.

Teresa Schmidt, Mavie Surau, Christoph Oster, Kathrin Kizina, Jana Grieger, Giorgio Cappello, Leon Jekel, Lazaros Lazaridis, Yahya Ahmadipour, Laurèl Rauschenbach and 9 more

Abstract readLetter
In one paragraph

Article in Journal of cancer research and clinical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Teresa SchmidtDepartment of Neurology and Center for Translational Neuro- and Behavioural Sciences (C-TNBS), Division of Clinical Neuro-Oncology, University Medicine Essen, University Duisburg-Essen, Hufelandstr 55, 45147, Essen, Germany.
Mavie SurauDepartment of Neurology and Center for Translational Neuro- and Behavioural Sciences (C-TNBS), Division of Clinical Neuro-Oncology, University Medicine Essen, University Duisburg-Essen, Hufelandstr 55, 45147, Essen, Germany.
Christoph OsterDepartment of Neurology and Center for Translational Neuro- and Behavioural Sciences (C-TNBS), Division of Clinical Neuro-Oncology, University Medicine Essen, University Duisburg-Essen, Hufelandstr 55, 45147, Essen, Germany.
Kathrin KizinaDepartment of Neurology and Center for Translational Neuro- and Behavioural Sciences (C-TNBS), Division of Clinical Neuro-Oncology, University Medicine Essen, University Duisburg-Essen, Hufelandstr 55, 45147, Essen, Germany.
Jana GriegerDepartment of Neurology and Center for Translational Neuro- and Behavioural Sciences (C-TNBS), Division of Clinical Neuro-Oncology, University Medicine Essen, University Duisburg-Essen, Hufelandstr 55, 45147, Essen, Germany.
Giorgio CappelloDepartment of Neurology and Center for Translational Neuro- and Behavioural Sciences (C-TNBS), Division of Clinical Neuro-Oncology, University Medicine Essen, University Duisburg-Essen, Hufelandstr 55, 45147, Essen, Germany.
Leon JekelDepartment of Neurology and Center for Translational Neuro- and Behavioural Sciences (C-TNBS), Division of Clinical Neuro-Oncology, University Medicine Essen, University Duisburg-Essen, Hufelandstr 55, 45147, Essen, Germany.
Lazaros LazaridisDepartment of Neurology, University Hospital Knappschaftskrankenhaus Bochum, Ruhr University Bochum, Bochum, Germany.
Yahya AhmadipourDepartment of Neurosurgery and Spine Surgery, Center for Translational Neuro- and Behavioural Sciences (C-TNBS),, University Medicine Essen, University Duisburg-Essen, Essen, Germany.
Laurèl RauschenbachGerman Cancer Consortium (DKTK), partner site Essen/Düsseldorf, a partnership between DKFZ and University Hospital Essen, Germany, DKFZ-Division Translational Neurooncology at the West German Cancer Center (WTZ), University Medicine Essen, University Duisburg-Essen, Essen, Germany.
Nika GuberinaDepartment of Radiotherapy, University Medicine Essen, University Duisburg-Essen, Essen, Germany.
Christoph PöttgenDepartment of Radiotherapy, University Medicine Essen, University Duisburg-Essen, Essen, Germany.
Kathy KeyvaniInstitute of Neuropathology, University Medicine Essen, University Duisburg-Essen, Essen, Germany.
Martin StuschkeDepartment of Radiotherapy, University Medicine Essen, University Duisburg-Essen, Essen, Germany.
Christoph KleinschnitzDepartment of Neurology and Center for Translational Neuro- and Behavioural Sciences (C-TNBS), Division of Clinical Neuro-Oncology, University Medicine Essen, University Duisburg-Essen, Hufelandstr 55, 45147, Essen, Germany.
Ulrich SureDepartment of Neurosurgery and Spine Surgery, Center for Translational Neuro- and Behavioural Sciences (C-TNBS),, University Medicine Essen, University Duisburg-Essen, Essen, Germany.
Andreas JunkerInstitute of Neuropathology, University Medicine Essen, University Duisburg-Essen, Essen, Germany.
Martin GlasDepartment of Neurology and Neurooncology, St. Marien Hospital, Lünen, Germany.
Sied KebirDepartment of Neurology and Center for Translational Neuro- and Behavioural Sciences (C-TNBS), Division of Clinical Neuro-Oncology, University Medicine Essen, University Duisburg-Essen, Hufelandstr 55, 45147, Essen, Germany. sied.kebir@uk-essen.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41946972
PMCPMC13057062

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.