Evidence map›Paper›PMID 41947426›Full record

Trial reportTheScientificWorldJournal2026

Effects of Snake Fruit-Infused Massage Oil With Traditional Thai Massage on Skin Quality: A Randomized Controlled Trial.

Suwipa Intakhiao, Warumpa Suwannarat, Thirapit Subongkot, Thanchanok Sirirak, Phannapat Piyaneeranat, Sukrisd Koowattanatianchai, Piyapong Prasertsri

Registry-linked trialAbstract readClinical Trial, Phase IIRandomized Controlled Trial
In one paragraph

Trial report in TheScientificWorldJournal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06227260 (Development and Evaluation of Body Massage Oil, Facial Mask, and Ready-to-drink Jelly From Snake Fruit), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06227260 phase2completednot on this map

Development and Evaluation of Body Massage Oil, Facial Mask, and Ready-to-drink Jelly From Snake Fruit (Salacca Edulis Reinw.)

TypeinterventionalSponsorBurapha UniversityRan2023 to 2023Enrolled178ConditionsBody Massage Oil From Snake Fruit, Facial Mask From Snake Fruit, Jelly From Snake FruitArmsThai massage, Thai massage with pure coconut oil, Thai massage with oil mixed with Snake fruit extract, Control, Facial mask with Snake fruit extract, Control jelly, Jelly with Snake fruit juice
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Suwipa IntakhiaoFaculty of Allied Health Sciences, Burapha University, Chonburi, Thailand, buu.ac.th.ORCID https://orcid.org/0009-0009-9461-3556
Warumpa SuwannaratFaculty of Allied Health Sciences, Burapha University, Chonburi, Thailand, buu.ac.th.ORCID https://orcid.org/0000-0003-3441-858X
Thirapit SubongkotFaculty of Pharmaceutical Sciences, Burapha University, Chonburi, Thailand, buu.ac.th.ORCID https://orcid.org/0000-0001-5980-2196
Thanchanok SirirakFaculty of Pharmaceutical Sciences, Burapha University, Chonburi, Thailand, buu.ac.th.ORCID https://orcid.org/0000-0002-9871-0494
Phannapat PiyaneeranatFaculty of Allied Health Sciences, Burapha University, Chonburi, Thailand, buu.ac.th.ORCID https://orcid.org/0000-0002-5703-8291
Sukrisd KoowattanatianchaiDivision of Cardiology, Department of Medicine, Burapha Hospital, Burapha University, Chonburi, Thailand, buu.ac.th.ORCID https://orcid.org/0000-0001-9404-8977
Piyapong PrasertsriFaculty of Allied Health Sciences, Burapha University, Chonburi, Thailand, buu.ac.th.ORCID https://orcid.org/0000-0003-2652-4622

Funding

Burapha UniversityNational Science Research and Innovation Fund (NSRF) 31/2566Thailand Science Research and Innovation
6 · The paper itself

Abstract

backgroundSalacca zalacca (snake fruit) is rich in antioxidants, polyphenols, organic acids, and vitamin C. This study aimed to evaluate the effectiveness of body massage oil containing snake fruit extract, in conjunction with traditional Thai massage (TTM), on skin quality in healthy individuals.

methodsSeventy-one participants aged 18-35 years were randomly assigned to one of three groups: (1) control group (n = 23) receiving TTM without oil; (2) Treatment-1 group (n = 23) receiving TTM with pure coconut oil; and (3) Treatment-2 group (n = 25) receiving TTM with snake fruit extract-infused oil. All participants received 60-min massages once weekly for 12 weeks. Skin parameters including elasticity, moisture, melanin, and oiliness were assessed at the neck, back, arm, and leg regions.

resultsAfter 12 weeks, skin elasticity significantly improved at all assessed regions in all groups (p < 0.001), with no significant between-group differences. Skin melanin levels significantly decreased at the back and leg regions across all groups (p < 0.05), with no between-group differences observed. Skin moisture significantly increased at the leg region only in the Treatment-2 group (p = 0.003). Skin oiliness significantly increased at all measured regions in both oil-based groups (Treatment-1 and Treatment-2) (p < 0.05) and was significantly higher than in the control group (p < 0.05), except at the back region in the Treatment-2 group.

conclusionMassage oil containing snake fruit extract demonstrated specific benefits in enhancing skin oiliness and localized moisture. However, it did not confer overall superiority over conventional coconut oil, while improvements in elasticity and melanin appeared to be primarily attributable to the massage technique itself.

trial registrationClinicalTrials.gov Identifier: NCT06227260.

Indexed as

FruitMassageMedicine, Thai TraditionalPlant ExtractsPlant OilsSkinSnakesAdolescentAdultAnimalsFemaleHumansMaleThailandYoung AdultPlant ExtractsPlant Oilsbody oilmassageskin healthsnake fruitspa

Identifiers

PMID41947426
PMCPMC13057404

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.